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Geographic Variation in Non-HCC MELD Exceptions and Its Effect on Liver Transplant Waitlist Outcomes

Organization UNIVERSITY OF ALABAMA AT BIRMINGHAMLocation BIRMINGHAM, UNITED STATESPosted 1 Jun 2021Deadline 31 Mar 2026 ⚠️
NIHUS FederalResearch GrantFY2025AccountingAddressAreaAwardCommunitiesCountryCountyCox Proportional Hazards ModelsDataDecrease disparityDiagnosisDisparitiesDisparityDistantEquityFaceFosteringFundingGeneralized GrowthGeographic AreaGeographic LocationsGeographic RegionGeographical LocationGeographyGoalsGrowthHealthHealth Catchment AreaHealth Service AreaHepatic TransplantationInvestigatorsKnowledgeLaboratoriesLiteratureLiverLiver GraftingLiver TransplantLocationLower disparityMentorsMethodsModelingOutcomePaintPatientsPersonalized medical approachPlayPoliciesPopulationPredictive FactorPrevalenceRegional DiseaseRegression AnalysesRegression AnalysisRegression DiagnosticsResearchResearch PersonnelResearchersRestRiskRisk EstimateRoleRunningRural AppalachiaRural AppalachianScientistService areaSideStandardizationStatistical RegressionSurgeonSystemTechniquesTestingTissue GrowthTrainingTransplantationVariantVariationWaiting Listsaccess differencesaccess to health careaccessibility of health careaccessibility to health careadvanced simulationanalytical methodcareerdeath riskdifferences in accessdisparity reductionend stage liver diseaseend stage liver failurefacesfacialgeographic differencegeographic disadvantagegeographic disparitygeographic inequalitygeographic inequitygeographic location disparitygeographic sitegeographic variationhealth care accesshealth care availabilityhealth care service accesshealth care service availabilityhepatic body systemhepatic organ systemhigh riskindividualized approachliver transplantationmitigate disparitymortalitymortality risknovelontogenypersonalized approachprecision approachreduce disparityreduction in disparityrole modelsimulationsocial health determinantssocial roletailored approachtransplantwaitlist

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Description preview

Summary: Geographic variation in model for end stage liver disease (MELD) scores at transplant across
donation service areas has fueled a major policy debate over allocation of donor livers. An important caveat to

this perceived disparity is the focus on allocation MELD, in which patients with lower calculated MELD scores

may be assigned a higher…

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