grant
Genetic and biochemical dissection of anterograde signaling for controlling plastid transcription
Organization UNIVERSITY OF CALIFORNIA RIVERSIDELocation RIVERSIDE, UNITED STATESPosted 7 Feb 2020Deadline 31 May 2028
NIHUS FederalResearch GrantFY2025ArabidopsisAssayAutoregulationBHLH ProteinBacteriophagesBasic HLH ProteinBasic Helix-Loop-Helix ProteinBasic Helix-Loop-Helix Transcription FactorsBioassayBiochemicalBiochemistryBioenergeticsBiogenesisBiological AssayBiological ChemistryCancersCell Communication and SignalingCell NucleusCell SignalingCellular biologyChloroplastsCommunicationComplexCoupledDNA-Dependent RNA PolymerasesDNA-Directed RNA PolymeraseDataDissectionEukaryotaEukaryoteEventFamilyGene ExpressionGene TranscriptionGenesGeneticGenetic ModelsGenetic TranscriptionGenetic studyGenomeGenomic approachGoalsHeterodimerizationHomeostasisHumanHuman PathologyIntracellular Communication and SignalingKnowledgeLaboratoriesLearningLightMalignant NeoplasmsMalignant TumorMediatingMissionMitochondriaModelingModern ManMolecularMolecular GeneticsNational Institutes of HealthNuclearNucleusOrganellesOrganismOrigin of LifeOutcomePhagesPhotoradiationPhotoreceptor CellPhotoreceptorsPhotosensitive CellPhotosynthesisPhysiological HomeostasisPhytochromePlantsPlastidsProteinsPublic HealthRNA ExpressionRNA PolymerasesRegulationRepressionResearchRoleSignal PathwaySignal TransductionSignal Transduction SystemsSignalingSystemTranscriptionTranscriptional ControlTranscriptional RegulationUnited States National Institutes of HealthVisual ReceptorWorkbacterial virusbiological signal transductioncell biologydisabilitygene productgenetic approachgenetic strategygenomic effortgenomic strategyhuman diseaseinnovateinnovationinnovativeinsightliving systemmalignancymitochondrialneoplasm/cancernovelphyB phytochromephyB proteinphytochrome Bprogramspromoterpromotorprotein complexrecruitsocial role
Description preview
Abstract
The control of organellar gene expression is critical for the cellular programming of all eukaryotic
organisms. While perturbing mitochondrial gene expression leads to human pathologies, including cancer,
altering plastid gene expression can kill plants. However, the cell signaling mechanisms that control
organellar gene expression remain…
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