grant
Gene and Variant Curation Expert Panels for Hearing Loss
Organization INDIANA UNIVERSITY INDIANAPOLISLocation INDIANAPOLIS, UNITED STATESPosted 1 Aug 2025Deadline 31 Jul 2028
NIHUS FederalResearch GrantFY2025Accuracy of DiagnosisAddressAllelesAllelomorphsAmericanAreaAuditoryBasic ResearchBasic ScienceCaringClassificationClinVarClinicalClinical EvaluationClinical ManagementClinical TestingClinical TrialsClinical geneticsCollaborationsCommunitiesCountryDNA TherapyDNA mutationDataData BasesDatabasesDepositDepositionDevelopmentDiagnosisDiagnosticDiseaseDisorderEducational workshopEffectivenessEnsureEvaluationExhibitsFundingGene AlterationGene MutationGene TargetingGene Transfer ClinicalGene variantGenesGeneticGenetic ChangeGenetic CounselingGenetic InterventionGenetic defectGenetic mutationGenomicsGoalsGuidelinesHealthHearing LossHeterogeneityHome PageHypoacusesHypoacusisIndividualInheritance PatternsInstitutionInternationalKnowledgeLaboratoriesMedical GeneticsMolecularMutationNIDCDNational Institute on Deafness and Other Communication DisordersNational Institutes of HealthOMIMOnline Mendelian Inheritance In ManOtolaryngologistOtolaryngologyOutcomePathogenicityPatient CarePatient Care DeliveryPersonsPhenotypePrevalenceProceduresPrognosisPublicationsPublishingRecommendationRecurrenceRecurrentResearchResearch ResourcesResourcesRisk EstimateScientific PublicationScientistSensory DisordersStandardizationStrategic PlanningStructureSystemSystematicsTherapeuticUnited States National Institutes of HealthVariantVariant Curation Expert PanelVariationWorkWorkshopallelic variantcare for patientscare of patientscaring for patientsclinical careclinical practiceclinical relevanceclinical testclinically relevantcustomized therapycustomized treatmentdata basedevelopmentaldiagnostic accuracydysfunctional hearingevidence basegene defectgene repair therapygene testinggene therapygene-based diagnosticsgene-based testinggene-based therapygenetic consultationgenetic counselorgenetic diagnosisgenetic diagnosticsgenetic disorder diagnosisgenetic hearing impairmentgenetic hearing lossgenetic testinggenetic therapygenetic variantgenetic-focused diagnosticgenome mutationgenome resourcegenomic data resourcegenomic resourcegenomic sequencing resourcegenomic therapygenomic varianthearing challengedhearing defecthearing deficienthearing deficithearing difficultyhearing dysfunctionhearing impairmenthereditary hearing impairmenthereditary hearing lossimprovedindividualized managementindividualized medicineindividualized patient managementindividualized patient treatmentindividualized therapeutic strategyindividualized therapyindividualized treatmentinherited hearing impairmentinherited hearing lossmedical collegemedical schoolsmeetingmeetingsmembermolecular pathologymultidisciplinarymutant alleleotorhinolaryngologypatient specific therapiespatient specific treatmentpersonalized clinical managementpersonalized diagnosispersonalized diagnosticspersonalized disease managementpersonalized managementpleiotropic effectpleiotropismpleiotropyprecise diagnosticsprecision diagnosticsprecision managementprecision medicineprecision-based medicineprognosticresearch clinical testingschool of medicinetailored medical treatmenttailored therapytailored treatmentunique treatmentwebinarwork groupworking group
Description preview
ABSTRACT
Hearing loss (HL) is the most common sensory disorder worldwide, with significant genetic, allelic, and
phenotypic heterogeneity. Due to its complexity, HL presents many challenges in diagnosis, management, and
treatment, with over 220 genes and 16,000 variants implicated in its nonsyndromic and common syndromic
forms. The Hearing Loss…
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