grant
Fundamental Studies and Applications of Tissue Sciences
Organization EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENTLocation UNITED STATES
NIHUS FederalResearch GrantFY2025AddressAffectAlimentary CanalAnionsArchitectureAreaBehaviorBindingBiologic ModelsBiologic TransportBiological FunctionBiological MimeticsBiological ModelsBiological ProcessBiological TransportBiomimeticsBiopolymersBody TissuesCalcium ionCalibrationCarbomer-940CartilageCartilaginous TissueCationsCell BodyCellsChargeChemicalsChemistryChondroitin SulfatesCollaborationsComplexDNADeoxyribonucleic AcidDevelopmentDiffusionDigestive TractDiseaseDisorderDivalent CationsDrug DeliveryDrug Delivery SystemsElasticityElectrostaticsElementsEngineering / ArchitectureEnvironmentExhibitsFoundationsGI TractGastrointestinal TractGastrointestinal tract structureGelGoalsH-bondHyaluronic AcidHydrationHydration statusHydrogelsHydrogen BondingHydrogen OxideHydrophobicityImageIonic StrengthsIonsIsraelKnowledgeLengthLungLung Respiratory SystemMR ImagingMR TomographyMRIMRIsMagnetic Resonance ImagingMath ModelsMeasurementMechanicsMedical Imaging, Magnetic Resonance / Nuclear Magnetic ResonanceMethodologyMethodsModel SystemModelingModulusMolecularMolecular ConfigurationMolecular ConformationMolecular Dynamics SimulationMolecular InteractionMolecular StereochemistryMolecular TransportMucinsMucus GlycoproteinMuscleMuscle TissueMusselsNMR ImagingNMR TomographyNa+ elementNatureNerveNeutronsNuclear Magnetic Resonance ImagingOrganismOsmosisOsmotic PressurePhasePhase TransitionPhysical condensationPhysicsPhysiologicPhysiologicalPlayPolymersPostdocPostdoctoral FellowPrecipitationProceduresProcessPropertyProteoglycanQuality ControlRelaxationResearch AssociateResistanceResolutionRoentgen RaysRoleScienceSeriesSpinal ColumnSpineStructureSwellingSystemTechniquesTemperatureTherapeuticThermodynamicThermodynamicsTimeTissue EngineeringTissue ModelTissuesTransport ProcessUniversitiesVertebral columnWaterX-RadiationX-Ray RadiationX-rayXrayZeugmatographyaggrecanalimentary tractbackbonebench bed sidebench bedsidebench to bed sidebench to bedsidebench to clinicbench to clinical practicebioengineered tissuebiological systemscarbopol 940computer based predictioncondensationconformationconformationalconformational stateconformationallyconformationscrosslinkdensitydesigndesigningdevelopmentaldiffuseddiffusesdiffusingdiffusionsdigestive canaldynamic systemdynamical systemengineered tissueenvironmental changeexperimentexperimental researchexperimental studyexperimentsflexibilityflexiblegenital tracthydrogen sulfate Chondroitinhydrophilicityimaginginsightinterestlight scatteringliving systemmacromoleculemathematic modelmathematical modelmathematical modelingmechanicmechanicalmechanical propertiesmodel designmolecular dynamicsmolecular massmuscularnew diagnosticsnext generation diagnosticsnovelnovel diagnosticsphysical chemical interactionphysical propertypolyacrylic acidpolyanionpolymerpolymericpost-docpost-doctoralpost-doctoral traineeprecipitationspredictive modelingpressurepreventpreventingprofessorquality assuranceregenerate new tissueregenerate tissueregenerating damaged tissueregenerating tissuereproductive tractresearch associatesresistantresolutionsresponsesocial rolesodium iontissue phantomtissue regenerationtissue regrowthtissue renewaltissue specific regenerationtranslational applicationsvan der Waals forceviscoelasticity
Description preview
The role of ions in biological systems is complex: they stabilize the local structures, and ion binding can also affect the intrinsic properties of the biopolymer molecules, such as flexibility, molecular conformation, and dynamics of polyelectrolyte chains with emphasis on the valence and chemical nature of the ion that governs the…
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