grant
Frequency domain speckle tracking for OCT based 3D vibrometry of the inner ear
Organization UNIVERSITY OF SOUTHERN CALIFORNIALocation Los Angeles, UNITED STATESPosted 30 Sept 2025Deadline 29 Sept 2028
NIHUS FederalResearch GrantFY202512 year old12 years of age3-D3-D structure3-Dimensional3-dimensional structure3D3D structureAddressAffectAlgorithmsAmericanAnatomic SitesAnatomic structuresAnatomyAnimal ModelAnimal Models and Related StudiesAnimalsApicalAutomobile DrivingBasilar MembraneBlebBlisterBody TissuesBullaBullous LesionCalibrationCapsulesCell Communication and SignalingCell SignalingCell membraneCellular MechanotransductionCochleaCochlear OrganComplexComputer softwareCytoplasmic MembraneDataDevelopmentDimensionsDoppler OCTEar CanalEnsureExternal Acoustic MeatusExternal auditory canalFrequenciesFutureGeneticHearingHearing LossHumanHypoacusesHypoacusisImageInner Hair CellsInner ear hair cellsInternal EarIntracellular Communication and SignalingIntracellular StructureLabyrinthLaser ElectromagneticLaser RadiationLasersMeasurementMeasuresMechanical Signal TransductionMechanicsMechanosensory TransductionMethodsMiceMice MammalsModelingModern ManMorphologyMotionMovementMurineMusNatural regenerationOCT TomographyOperative ProceduresOperative Surgical ProceduresOptical Coherence TomographyOpticsOrganOuter Hair CellsPatternPerformancePeriodicalsPersonsPhasePlasma MembranePositionPositioning AttributePrevalencePreventative therapyPreventive therapyProceduresProcessRegenerationResearchResolutionRotationSamplingScanningSeriesSignal TransductionSignal Transduction SystemsSignalingSoftwareSpeedStimulusStructureSubcellular structureSurfaceSurgicalSurgical InterventionsSurgical ProcedureSystemTechniquesTechnologyTimeTissuesUnited StatesValidationVesicationWorkage 12 yearsarmbiological signal transductionbody movementbonecapsulecurative interventioncurative therapeuticcurative therapycurative treatmentsdevelopmentaldrivingdysfunctional hearingexperimentexperimental researchexperimental studyexperimentsgood hearinghealthy hearinghearing challengedhearing defecthearing deficienthearing deficithearing difficultyhearing dysfunctionhearing impairmenthearing loss therapyhearing loss treatmentimage-based methodimagingimaging in miceimaging in vivoimaging methodimaging modalityimaging studies for miceimaging studies in miceimaging systemimprovedin vivoin vivo imaginginner earinsightmechanicmechanicalmechanosensingmechanotransductionmice imagingmiddle earmodel of animalmurine imagingnew approachesnormal hearingnovel approachesnovel strategiesnovel strategyopticaloptical Doppler tomographyoptical coherence Doppler tomographyperiodicperiodicalplasmalemmaregenerateresolutionsresponsesensorsoundspatial and temporalspatial temporalspatiotemporalsurgerytectorial membranethree dimensionalthree dimensional structuretooltreatment for hearing losstrendtwelve year oldtwelve years of agevalidationsvectorvibration
Description preview
The increasing prevalence of hearing loss is driving the demand for improved techniques to study the intricate
structure and complex processes of the living cochlea. Optical coherence tomography (OCT) has become a
widely used technology to study the vibrometry of the living cochlea due to its temporal and spatial resolution.
One limitation with…
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