grant
Formation of the Drosophila salivary gland
Organization JOHNS HOPKINS UNIVERSITYLocation BALTIMORE, UNITED STATESPosted 1 Feb 2001Deadline 31 Jan 2028
NIHUS FederalResearch GrantFY20262-dimensional3-D3-Dimensional3DAcuteAddressAffectApicalArchitectureAutoregulationBasal Transcription FactorBasal transcription factor genesBindingBinding SitesBiologic ModelsBiological ModelsBody TissuesCancersCell BodyCell DeathCell ShapeCellsCessation of lifeChromatinCombining SiteConsensusDNA BindingDNA Binding InteractionDNA boundDNA mutationDeathDevelopmentDrosophilaDrosophila genusEmbryoEmbryonicEngineering / ArchitectureEnhancersEpitheliumEventFamilyFamily memberFertilized EggFertilized OvumForegutGene ExpressionGeneral Transcription Factor GeneGeneral Transcription FactorsGenesGeneticGenetic ChangeGenetic defectGenetic mutationHeadHindgutHistonesHomeostasisHumanHuman DevelopmentIntegral Membrane ProteinIntrinsic Membrane ProteinJobsKidneyKidney Urinary SystemLearningLipidsLiverLiver necrosisLungLung Respiratory SystemMaintenanceMalignant NeoplasmsMalignant TumorMammaliaMammalsMapsMechanicsMediatingMetabolic DiseasesMetabolic DisorderModel SystemModelingModern ManMolecularMolecular InteractionMorphogenesisMorphologyMotorMutationMyosin IIMyosin Type IINecrosis hepatocellularNucleic AcidsOccupationsOrganOrgan SizeOspPancreasPancreaticParticipantPhysiologicPhysiologicalPhysiological HomeostasisPhysiologyPlayPositionPositioning AttributePrimitive foregut structureProfessional PositionsProteinsReactive SiteRegulationRegulatory PathwayRegulatory ProteinRepressionRoleSalivary GlandsShapesSiteSpecific qualifier valueSpecifiedTestingThesaurismosisTimeTissuesTranscription Factor Proto-OncogeneTranscription factor genesTransmembrane ProteinTransmembrane Protein GeneTubeWinged HelixWorkdevelopmentalfitnessfruit flygenetic regulatory proteingenome mutationgland developmenthepatic body systemhepatic necrosishepatic organ systemliver-specific proteinmalignancymechanicmechanicalmetabolism disordermigrationmorphogenetic processmutantnecrocytosisneoplasm/cancernon-muscle myosinnonmuscle myosinorgan developmentorgan growthouter surface lipoproteinpreventpreventingprotein functionrecruitregulatory gene productrenalsocial rolesugarthree dimensionaltooltranscription factortwo-dimensionalvertebrate embryoszygote
Description preview
The FoxA family of winged-helix DNA-binding transcription factors (TFs) play major roles in the
development of many organs in vertebrate embryos. In some cases, they are proposed to be
determinants of specific cell fates because they are expressed early and continuously in forming
organs, and they are capable of what has been referred to as…
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