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Factors of Resilience to Alzheimers Disease and Related Dementias among Latinx: The Role of Bilingualism
Organization COLUMBIA UNIVERSITY HEALTH SCIENCESLocation NEW YORK, UNITED STATESPosted 1 May 2020Deadline 30 Jun 2025 β οΈ
NIHUS FederalResearch GrantFY202521+ years oldAD related dementiaADRDAdultAdult HumanAgeAgingAlzheimer risk factorAlzheimer's and related dementiasAlzheimer's dementia and related dementiaAlzheimer's dementia or related dementiaAlzheimer's disease and related dementiaAlzheimer's disease and related disordersAlzheimer's disease or a related dementiaAlzheimer's disease or a related disorderAlzheimer's disease or related dementiaAlzheimer's disease related dementiaAlzheimer's disease riskAmyloidAmyloid SubstanceAttentionBiological MarkersBrainBrain Nervous SystemBrain Vascular DisordersBuffersCaliforniaCerebrovascular DiseaseCerebrovascular DisordersClinicalCognitionCognitiveCognitive DisturbanceCognitive ImpairmentCognitive agingCognitive declineCognitive function abnormalCommunitiesCross Sectional AnalysisCross-Sectional AnalysesCross-Sectional StudiesCross-Sectional SurveyDataData AnalysesData AnalysisDecrease disparityDifferences between sexesDiffers between sexesDisease Frequency SurveysDisparitiesDisparityDisturbance in cognitionEducationEducational aspectsEncephalonEnrollmentEnvironmental FactorEnvironmental Risk FactorExclusionFamilyFoundationsFrequenciesGoalsGroups at riskHealth Care SystemsHeightHispanic PopulationsHispanic groupHispanic individualHispanic peopleHispanicsHomeImmigrantImmigrationImpaired cognitionInterventionIntracranial Vascular DiseasesIntracranial Vascular DisordersInvestigatorsKnowledgeLanguageLatineLatinxLatinx groupLatinx individualLatinx peopleLatinx populationLong-term cohortLongitudinal cohortLower disparityMR ImagingMR TomographyMRIMRIsMT-bound tauMagnetic Resonance ImagingMeasurementMedical Imaging, Magnetic Resonance / Nuclear Magnetic ResonanceMethodologyMethodsModelingNMR ImagingNMR TomographyNerve DegenerationNeuron DegenerationNeuropsychologiesNeuropsychologyNon-HispanicNonhispanicNot Hispanic or LatinoNuclear Magnetic Resonance ImagingOutcomePETPET ScanPET imagingPETSCANPETTPathologyPeople at riskPersons at riskPhasePopulationPopulation HeterogeneityPopulations at RiskPositron Emission Tomography Medical ImagingPositron Emission Tomography ScanPositron-Emission TomographyProxyPsycholinguisticsRad.-PETReportingResearchResearch PersonnelResearchersRiskRoleSex DifferencesSexual differencesSocio-economic statusSocioeconomic StatusStatistical MethodsSymptomsTrainingUniversitiesWashingtonZeugmatographyadulthoodagesalzheimer riskbilingualbilingualismbio-markersbiologic markerbiomarkerbrain atrophybrain vascular diseasebrain vascular dysfunctioncareercerebral atrophycerebral vascular diseasecerebral vascular dysfunctioncerebrovascular dysfunctioncognitive assessmentcognitive changecognitive dysfunctioncognitive functioncognitive losscognitive neurosciencecognitive reservecognitive testingcohortcompare to controlcomparison controlcortical atrophydata harmonizationdata interpretationdementia riskdisparity in healthdisparity reductiondiverse populationsenrollenvironmental riskexecutive controlexecutive functionexperienceharmonized datahealth disparityheterogeneous populationhomesimaging biomarkerimaging markerimaging-based biological markerimaging-based biomarkerimaging-based markerintracranial vascular dysfunctionmicrotubule bound taumicrotubule-bound taumid lifemid-lifemiddle agemiddle agedmidlifemitigate disparityneural degenerationneural imagingneuro-imagingneurodegenerationneurodegenerativeneuroimagingneuroimaging biomarkerneuroimaging markerneurological degenerationneurological imagingneuronal degenerationneuropathologicneuropathologicalneuropathologyneuropsychologicnoveloffspringold agepopulation diversitypositron emission tomographic (PET) imagingpositron emission tomographic imagingpositron emitting tomographypreservationprotective effectprotective factorsrecruitreduce disparityreduction in disparityresilienceresilience factorresiliency factorresilientrisk factor for dementiarisk for dementiasexsex based differencessex-dependent differencessex-related differencessex-specific differencessocial cultural factorsocial culturesocial culture determinantsocial rolesocio-culturalsocio-economic positionsocioculturalsociocultural determinantsociocultural factorsocioeconomic positionstatistic methodstautau Proteinstau factorΟ Proteins
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Project Summary/Abstract
As the population ages, Latinx communities, families, and healthcare systems will be confronted by the
growing crisis of Alzheimer's disease and related dementias (ADRD). Identifying factors that confer resilience
to ADRD among aging Latinx communities is of critical importance to successfully reduce disparities. Someβ¦
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