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Expansion Microscopy

Organization MASSACHUSETTS INSTITUTE OF TECHNOLOGYLocation CAMBRIDGE, UNITED STATESPosted 15 Jul 2017Deadline 31 Jan 2026 ⚠️
NIHUS FederalResearch GrantFY2025BindingBiologic PreservationBiologicalBiological PreservationBiologyBody TissuesBrain MappingCell BodyCell ComponentsCell StructureCellsCellular StructuresChemicalsCommunitiesComplexConsumptionCryo-electron MicroscopyCryoelectron MicroscopyDemocracyDevelopmentDiamondDiseaseDisorderEducational workshopElectron CryomicroscopyElectron MicroscopyEquipmentFluorescent ProbesFree RadicalsGoalsGrantHigh temperature of physical objectHumanHydrogelsHydrogen OxideImageInternetLabelLipidsMapsMedicalMethodsMicroscopeMicroscopyModern ManMolecular InteractionNon-Polyadenylated RNANucleic AcidsPaperParaffin EmbeddingPersonsPolymersPrintingProcessProteinsProtocolProtocols documentationRNARNA Gene ProductsReagentResearchResearch SpecimenResolutionResource SharingRibonucleic AcidSamplingShapesSpecimenSpecimen HandlingSpecimen ProcessingSpeedSwellingTechnologyTimeTissuesTrainingVisualizationWWWWaterWorkWorkshopbiologicbiological systemscell imagingcell typecellular imagingcold temperaturecryo-EMcryoEMcryogenic electron microscopydevelopmentalhigh temperaturehuman tissueimage-based methodimagingimaging methodimaging modalityinsightinventionlow temperaturenano meter scalenano meter sizednanoimagingnanometer scalenanometer sizednanoscalenew drug targetnew druggable targetnew pharmacotherapy targetnew therapeutic targetnew therapy targetnovel drug targetnovel druggable targetnovel pharmacotherapy targetnovel therapeutic targetnovel therapy targetpolymerpolymericpreservationresolutionsscale upskillssuper high resolutionsuperresolutionsuperresolution microscopytech developmenttechnology developmentultra high resolutionwebworld wide web

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Description preview

Biomolecules, such as nucleic acids, lipids, and proteins, are nanoscale in size, and often localized with
nanoscale precision with respect to each other, and to cellular structures. Analyzing the nanoscale

configurations of biomolecules in cells and tissues is critical for understanding how they work, as well as how

they go wrong in disease…

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Expansion Microscopy β€” MASSACHUSETTS INSTITUTE OF TECHNOLOGY | UNITED STATES | Jul 2017 | Dev Procure