grant
Excitation and Inhibition in Neural Circuits of the Visual Cortex
Organization UNIVERSITY OF CALIFORNIA BERKELEYLocation BERKELEY, UNITED STATESPosted 1 Sept 2013Deadline 31 May 2029
NIHUS FederalResearch GrantFY20252-photonArchitectureBrainBrain Nervous SystemCalciumCell BodyCellsCerebral cortexConnector NeuronCyclic SomatostatinD CellsDataDelta CellDependenceDetectionElectrophysiologyElectrophysiology (science)EncephalonEngineering / ArchitectureEquilibriumExhibitsFeedbackFire - disastersFiresGoalsGrowth Hormone Inhibiting FactorsGrowth Hormone-Inhibiting HormoneHolographyImageIntercalary NeuronIntercalated NeuronsInterneuronsInternuncial CellInternuncial NeuronKnowledgeLateralLinkLocationMapsMeasuresMediatingMiceMice MammalsModelingMurineMusNerve CellsNerve UnitNervous System DiseasesNervous System DisorderNeural CellNeurocyteNeurologic DisordersNeurological DisordersNeuronsNeurophysiology / ElectrophysiologyPatternPerceptionPlayPopulationPrimary visual cortexProbabilityProcessPropertyPyramidal CellsRecurrenceRecurrentRoleSRIHSRIH-14SensorySightSomatostatinSomatostatin CellsSomatostatin Secreting CellSomatostatin-14Somatotropin Release Inhibiting FactorsSomatotropin Release-Inhibiting HormoneStimulusStriate CortexStriate areaSynapsesSynapticTestingV1 neuronVisionVisualVisual CortexVisual FieldsVisual PerceptionWorkarea striataawakebalancebalance functionelectrophysiologicalexperimentexperimental researchexperimental studyexperimentsextrastriate areaextrastriate cortexextrastriate visual cortexeye fieldfireflexibilityflexiblegrowth hormone release inhibiting factorimagingimaging Segmentationin vivoinsightmodel buildingneuralneural circuitneural circuitryneurocircuitryneurological diseaseneuronalnovelobject recognitionoptogeneticsorientation preferenceorientation selectivitypatch clamppostsynapticpresynapticpreventpreventingreceptive fieldresponsesegregationsocial rolesynapsesynaptic circuitsynaptic circuitrytwo-photonvisual areavisual corticalvisual excitationvisual functionvisual stimulus
Description preview
Project Summary
Neural circuits of the primary visual cortex (V1) are critical for generating perceptions of our external world. In
V1, most neurons exhibit potent modulation by stimuli that are outside their receptive fields, a process termed
`surround modulation'. Importantly, the magnitude and sign of surround modulation depend on the…
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