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Exacerbation of Colitis by Enterobacteriaceae

Organization UNIVERSITY OF CALIFORNIA AT DAVISLocation DAVIS, UNITED STATESPosted 15 Jan 2015Deadline 31 Mar 2026 ⚠️
NIHUS FederalResearch GrantFY20252-Hydroxybenzoic AcidAnaerobic BacteriaAnimal ModelAnimal Models and Related StudiesAnti-InflammatoriesAnti-Inflammatory AgentsAnti-inflammatoryAntibiotic TherapyAntibiotic TreatmentAutomobile DrivingAutoregulationBacteriaBioenergeticsBionomicsChildhoodColiform BacilliColitisColonComplexDataDiseaseDisorderDrugsEcologic SystemsEcological SystemsEcologyEcosystemEnteric BacteriaEnterobacteriaEnterobacteriaceaeEnvironmentEnvironmental FactorEnvironmental Risk FactorEpithelial CellsEpitheliumExposure toFamily memberFermentationFiberFoundationsFundingGI microbiotaGastrointestinal microbiotaGeneralized GrowthGenetic predisposing factorGoalsGrowthH2O2HealthHomeostasisHumanHydrogen PeroxideHydroperoxideHypoxiaHypoxicInflammationIntermediary MetabolismJournalsMagazineMediatingMedicationMetabolic ProcessesMetabolismMiceMice MammalsMitochondriaModern ManMucosaMucosal TissueMucous MembraneMucous body substanceMucusMurineMusNutritionOutcomeOxidative PhosphorylationOxidative Phosphorylation PathwayOxygen ConsumptionOxygen DeficiencyPathogenesisPharmaceutical PreparationsPhysiological HomeostasisProductivityPublicationsResearchSalicylic AcidsScientific PublicationSecondary toSolidSurfaceTestingTissue GrowthUlcerated ColitisUlcerative ColitisWorkabsorptionanaerobebacterial disease treatmentbacterial infectious disease treatmentbowel inflammationcolon microbescolon microbial communitycolon microbiotacolonic microbiotacommunity microbesdrivingdrug/agentdysbacteriosisdysbiosisdysbioticenteric microbial communityenteric microbiotaenvironmental riskexpectationexperimentexperimental researchexperimental studyexperimentsgastrointestinal microbial floragenetic risk factorgut communitygut floragut homeostasisgut inflammationgut microbe communitygut microbial communitygut microbial compositiongut microbial consortiagut microbiotagut microbioticgut microflorahost-associated microbeshost-associated microbial communitieshost-associated microbiotahost-associated microorganismsinflamed bowelinflamed gutinflamed intestineinherited factorinnovateinnovationinnovativeintestinal floraintestinal inflammationintestinal microbiotaintestinal microfloraintestinal tract microfloraknowledge of resultsmicrobe communitymicrobialmicrobial communitymicrobial consortiamicrobial floramicrobial imbalancemicrobiotamicrofloramicroorganism communitymitochondrialmodel of animalmucosa-associated microbesmucosa-associated microbial communitymucosa-associated microbiotamucosal floramucosal microbesmucosal microbiotamucosal microfloramucousmultispecies consortiao-Hydroxybenzoic Acidontogenyortho-Hydroxybenzoic Acidpediatricpolymicrobial communitypublic health relevancesalicylatesoundtool

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Description preview

ABSTRACT
Ulcerative colitis is a complex disease caused by a combination of genetic risk factors,
childhood exposure to environmental risk factors and a poorly defined microbiota component.
Ulcerative colitis is associated with imbalance in the microbiota (dysbiosis) characterized by
increased Enterobacteriaceae and reduced Clostridia abundance.…

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