grant

Evolving together, evolving apart: probing the genomic basis of a facultative host-microbe mutualism

Organization PENNSYLVANIA STATE UNIVERSITY, THELocation UNIVERSITY PARK, UNITED STATESPosted 9 Mar 2026Deadline 28 Feb 2031
NIHUS FederalResearch GrantFY2026AtmosphereBacteriaBacterial GenesBiologic ModelsBiological ModelsCollectionDevelopmentEnvironmentEvolutionExposure toGene FrequencyGenerationsGenesGeneticGenomicsGoalsHair RootHealthHistoryInvadedKnowledgeLeadMedicago truncatulaMethodsMicrobeModel SystemMonitorNatureNitrogenNoduleOrganismPb elementPhotosynthesisPlant GenesPlantsPlayPopulationRecording of previous eventsResearchRewardsRhizobium melilotiRoleS melilotiS. melilotiSinorhizobium melilotiSoilStructureSymbiosisSystemTimeUniversitiesValidationVariantVariationWorkallelic frequencybacterial fitnessbeneficial florabeneficial microbesbeneficial microflorabeneficial microorganismbio-informatics toolbioinformatics toolcommensalismcost effectivedevelopmentalentire genomefitnessfull genomefundamental researchgene functiongenome sequencingheavy metal Pbheavy metal leadhistorieshost microbe associationhost microbe relationshiphost-microbe interactionshost-microbial interactionshost-microorganism interactionsimprovedinnovateinnovationinnovativeinsightlab assignmentlab experimentlaboratory activitylaboratory assignmentlaboratory exerciselaboratory experimentliving systemmicrobialmicrobial hostmutualismmutualistic interactionspathogenprogramssocial rolesugartoolvalidationswhole genome
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Project Summary
The Burghardt lab at Penn State University studies the evolution of host-microbe mutualisms. Unlike

obligate pathogens, mechanisms and rules governing facultative, mutualistic symbiosis remain largely

unexplored. These relationships are characterized by the ability of each partner to survive independently, live

in close physical…

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