grant
Evaluating the Impact of Non-COPD Medications on COPD Management
Organization BRIGHAM AND WOMEN'S HOSPITALLocation BOSTON, UNITED STATESPosted 17 Sept 2024Deadline 30 Jun 2029
NIHUS FederalResearch GrantFY2025AccelerationAddressAgeAgonistAlgorithmsCOPDChronic Obstruction Pulmonary DiseaseChronic Obstructive Lung DiseaseChronic Obstructive Pulmonary DiseaseClinicalCollectionComputational toolkitDataData ReportingData SourcesDermatologyDiabetes MellitusDimethylbiguanidineDimethylguanylguanidineDiseaseDisease ManagementDisease OutcomeDisorderDisorder ManagementDrugsElectronic Health RecordEthnic OriginEthnicityEvaluationFoundationsFutureGLP-1 receptorGLP-I receptorGoalsHealth CareHealth Insurance for Aged and Disabled, Title 18Health Insurance for Disabled Title 18HeterogeneityIMiDImmune modulatory therapeuticIndividualInfrastructureInvestigationInvestigatorsKnowledgeLinkLiteratureMeasurementMedicareMedicationMetforminMethodologyMethodsMonitorMorbidityMorbidity - disease rateN,N-dimethyl-imidodicarbonimidic diamideObservation researchObservation studyObservational StudyObservational researchOutcomePatient CarePatient Care DeliveryPatientsPatternPharmaceutical EpidemiologyPharmaceutical PreparationsPharmacoepidemiologyPhenotypePositionPositioning AttributePreventionRaceRacesRandomized, Controlled TrialsReportingResearch PersonnelResearchersRheumatologyScientific Advances and AccomplishmentsSeverity of illnessSmokerSubgroupTestingTherapeuticTimeTitle 18UpdateWorkagesbeneficiarycare for patientscare of patientscaring for patientschronic obstructive pulmonary disorderco-morbidco-morbiditycohortcomorbiditycomparative effectivenesscomputational toolboxcomputational toolscomputational toolsetcomputerized toolsdata infrastructuredata representationdata representationsdiabetesdisease phenotypedisease severitydisease subgroupsdisease subtypedisorder subtypedrug discoverydrug epidemiologydrug repositioningdrug repurposingdrug/agentelectronic health care recordelectronic health dataelectronic health medical recordelectronic health plan recordelectronic health registryelectronic medical health recordglucagon-like peptide-1 receptorhealth datahealth insurance for disabledimmune modulating agentsimmune modulating drugimmune modulating therapeuticsimmune modulatory agentsimmune modulatory drugsimmunomodulating agentsimmunomodulating drugsimmunomodulator agentimmunomodulator drugimmunomodulator medicationimmunomodulator prodrugimmunomodulator therapeuticimmunomodulatory agentsimmunomodulatory drugsimmunomodulatory therapeuticsimprovedinsurance claimsmortalitymultiple data sourcesnew drug targetnew drug treatmentsnew druggable targetnew drugsnew pharmacological therapeuticnew pharmacotherapy targetnew therapeutic targetnew therapeuticsnew therapynew therapy targetnext generation therapeuticsnovel drug targetnovel drug treatmentsnovel druggable targetnovel drugsnovel pharmaco-therapeuticnovel pharmacological therapeuticnovel pharmacotherapy targetnovel therapeutic targetnovel therapeuticsnovel therapynovel therapy targetpatient subclasspatient subclusterpatient subgroupspatient subpopulationspatient subsetspatient subtypespharmacoepidemiologicpharmacoepidemiologicalphenotypic datapopulation basedracialracial backgroundracial originrandomized control trialrandomized, clinical trialsrepurposing agentrepurposing medicationscientific accomplishmentsscientific advancessextreatment effect
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Description preview
Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide. While
numerous scientific advances have been made to improve the care of patients with COPD, current therapeutic
options remain limited. The growing availability of electronic health data and new computational tools have
brought an unprecedented…
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