Equipment Upgrade for a 7T Preclinical MRI Scanner at UC Davis

PROJECT SUMMARY/ABSTRACT
This shared instrumentation grant proposal seeks funding to upgrade the Bruker 7T preclinical MRI system at
the UC Davis Center for Molecular and Genomic Imaging (CMGI), a vital resource supporting a broad community
of NIH-funded investigators. The current Bruker AVANCE III console, installed in 2010, has reached end-of-life,
with no guaranteed vendor support and limited spare parts, placing the system at significant risk for prolonged
downtime. This vulnerability threatens a diverse portfolio of NIH-funded research at UC Davis, encompassing
cancer biology, neuroscience, cardiometabolic disease, immunology, molecular imaging, translational
nanomedicine, and multi-modal studies integrating MRI with PET and optical imaging. Upgrading to the fully
supported AVANCE NEO console is essential to ensure continuity and reliability for these critical research
programs. Seamless compatibility with the existing Bruker 7T magnet will enable a smooth transition, minimizing
disruption to ongoing studies. With CMGI’s specialized infrastructure and technical expertise in in vivo preclinical
imaging, and strong institutional backing for robust operation and long-term maintenance, this upgrade will not
only safeguard current research but also empower UC Davis investigators to pursue innovative biomedical
studies and accelerate the translation of preclinical discoveries into clinical advances.

Grant Number: 1S10OD040238-01
NIH Institute/Center: NIH
Principal Investigator: Abhijit Chaudhari