grant

Epidemiology of racial differences in decision making among older adults

Organization RUSH UNIVERSITY MEDICAL CENTERLocation CHICAGO, UNITED STATESPosted 15 Sept 2018Deadline 30 Jun 2026
NIHUS FederalResearch GrantFY202265+ years oldAD dementiaAfrican American groupAfrican American individualAfrican American peopleAfrican American populationAfrican AmericansAged 65 and OverAgingAlzheimerAlzheimer Type DementiaAlzheimer diseaseAlzheimer risk factorAlzheimer sclerosisAlzheimer syndromeAlzheimer'sAlzheimer's DiseaseAlzheimer's disease dementiaAlzheimer's disease riskAlzheimers DementiaAlzheimers diseaseAmentiaApplication ContextBasic ResearchBasic ScienceBlood Coagulation Factor IBlood Coagulation Factor OneBlood Factor OneCoagulation Factor ICoagulation Factor OneCognitionCognitiveCognitive DisturbanceCognitive ImpairmentCognitive declineCognitive function abnormalComplexDataDecision MakingDecrease health disparitiesDementiaDisturbance in cognitionElderlyEpidemiologyFactor IFactor OneFibrinogenFraudGoalsHealthHealth disparity mitigationHealth disparity reductionImpaired cognitionInternetInterventionIntervention StrategiesKnowledgeLength of LifeLifeLinkLongevityLower health disparitiesMediatingMemoryMinorityMitigate health disparitiesModelingOutcomeParticipantPathway interactionsPersonal SatisfactionPredispositionPrimary Senile Degenerative DementiaPsychosocial FactorPublic HealthRaceRacial GroupRacial StocksReduce health disparitiesResearchResearch ResourcesResourcesRiskSocio-economic statusSocioeconomic StatusSusceptibilityTestingTranslational ResearchTranslational ScienceTrustVictimizationWWWWorkadvanced ageage 65 and greaterage 65 and olderaged 65 and greateraged ≥65alzheimer riskcognitive abilitycognitive dysfunctioncognitive functioncognitive losscontextual factorsdementia of the Alzheimer typedemographicsdisabilitydiscountingdisparity in healtheldersepidemiologicepidemiologicalexperienced discriminationfinancial literacygeriatrichealth disparityhealth economicshealth literacyhuman old age (65+)interventional strategylate lifelater lifelife spanlifespanmild cognitive disordermild cognitive impairmentmortalitynew approachesnew therapeutic approachnew therapeutic interventionnew therapeutic strategiesnew therapy approachesnovel approachesnovel strategiesnovel strategynovel therapeutic approachnovel therapeutic interventionnovel therapeutic strategiesnovel therapy approachold ageolder adultolder personpathwayperceived discriminationperception of discriminationprimary degenerative dementiapsychological distresspsychosocialpsychosocial resourcespsychosocial variablesrace differencesracial differencerate of changeresearch studyresponseself-reported discriminationsenile dementia of the Alzheimer typesenior citizensocio-economic positionsocioeconomic positionsoundtranslation researchwebwell-beingwellbeingworld wide web
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Full Description

ABSTRACT
Sound decision making is important for maintaining independence and well-being across the lifespan but is

critical in old age, when some of life’s most complex and impactful decisions are made. Recent work from our

group and others has shown that decision making requires cognitive, contextual and psychosocial resources

and that many older persons—even those without cognitive impairment—are vulnerable to poor decision

making in key domains such as finance and health and frequently become victims of fraud. Poor decision

making in aging predicts several adverse health outcomes including Alzheimer’s disease, incident mild

cognitive impairment and mortality and poses a major public health and economic challenge. Importantly,

however, most of the research on decision making to date has involved White participants. Relatively little is

known about decision making among African Americans, despite well documented racial differences in the

cognitive, contextual (e.g., socioeconomic status) and psychosocial (e.g., psychological distress) resources

that influence decision making. Building on our conceptual model of decision making in aging and compelling

preliminary data that suggest racial differences, we hypothesize that racial differences in decision making

contribute to disparities in health outcomes and that contextual and psychosocial factors account for these

differences. The goal of the proposed study, submitted in response to PAR-16-448, is to elucidate the

determinants and adverse health consequences of racial differences in decision making. This study will

leverage the unique resources of an ongoing study of African Americans, the Minority Aging Research Study,

to collect new longitudinal data on multiple aspects of decision making (i.e., financial and health decision

making, temporal discounting, scam susceptibility, fraud victimization) and related contextual and psychosocial

factors in 600 older African Americans without dementia. These newly collected data will be linked with

identical longitudinal decision making data already available from an ongoing study of more than 1,100 Whites

from the Memory and Aging Project to support analyses of: 1) racial differences in decision making among

African Americans and Whites matched on demographics and cognition, 2) the contextual and psychosocial

factors that drive them, and 3) the degree to which racial differences in decision making contribute to

disparities in health. Thus, this study is uniquely poised to efficiently identify the determinants and public health

impact of racial differences in decision making and will facilitate new therapeutic approaches to promote

independence, health and well-being among diverse older persons.

Grant Number: 5R01AG060376-05
NIH Institute/Center: NIH

Principal Investigator: PATRICIA BOYLE

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