grant

Electrophysiological biomarkers of social engagement in autism

Organization DUKE UNIVERSITYLocation DURHAM, UNITED STATESPosted 1 Sept 2024Deadline 31 Aug 2028
NIHUS FederalResearch GrantFY20250-11 years old6 year old6 years of ageASDActive Follow-upAffectAutismAutistic DisorderBackBehaviorBehavioralBiological MarkersBrainBrain Nervous SystemCOBRECare GiversCaregiversCenter of Biomedical Research ExcellenceCenters of Research ExcellenceCharacteristicsChildChild PsychiatryChild YouthChildren (0-21)Clinical ResearchClinical StudyClinical TrialsClinical assessmentsCodeCoding SystemCoupledDataDetectionDevelopmentDoctor of PhilosophyDorsumEEGEarly DiagnosisEarly Infantile AutismEarly InterventionEarly intervention trialsElectroencephalogramElectroencephalographyElectrophysiologyElectrophysiology (science)EncephalonEnvironmentEyeEyeballFamilyFoundationsFundingFutureGoalsGrantHeterogeneityHumanIndividualIndividual DifferencesInfantile AutismInfrastructureInterdisciplinary ResearchInterdisciplinary StudyInterventionJointsKanner's SyndromeKnowledgeLeadLearningMachine LearningMeasuresMental disordersMental health disordersMentorsMentorshipMethodological StudiesMiceMice MammalsModelingModern ManMultidisciplinary CollaborationMultidisciplinary ResearchMurineMusNIMHNational Institute of Mental HealthNational Institutes of HealthNeurophysiology / ElectrophysiologyNeurosciencesNeurosciences ResearchOutcome MeasureParticipantPatternPb elementPh.D.PhDPhysiciansPopulationPre-Clinical ModelPreclinical ModelsProductivityPsychiatric DiseasePsychiatric DisorderPsychiatristPsychiatryResearchResearch PrioritySchemeScientistSocial DevelopmentSocial InteractionSocial skills developmentStandardizationStatistical Data AnalysesStatistical Data AnalysisStatistical Data InterpretationStatistical MethodsStimulusStratificationSupervisionTestingTimeTrainingTranslational ResearchTranslational ScienceTranslationsUnited States National Institutes of HealthUniversitiesVariantVariationWorkactive followupage 6 yearsautism modelautism spectral disorderautism spectrum disorderautisticautistic childrenautistic individualsautistic peopleautistic spectrum disorderbio-markersbiologic markerbiomarkerbiomarker identificationbrain basedcareercareer developmentchildren on the autism spectrumchildren with ASDchildren with autismchildren with autism spectrum disorderclinical relevanceclinically relevantconnectomecritical perioddesigndesigningdevelopmentalearly childhoodearly detectionearly-career facultyelectrophysiologicalendophenotypeexperiencefollow upfollow-upfollowed upfollowupfunctional improvementgazeheavy metal Pbheavy metal leadidentification of biomarkersidentification of new biomarkersimprove functionimprovedimproved functional outcomesindividuals on the autism spectrumindividuals on the spectrumindividuals with ASDindividuals with autismindividuals with autism spectrum disorderinterpersonal competenceinterpersonal competencykidsmachine based learningmachine learning based methodmachine learning methodmachine learning methodologiesmarker identificationmeasurable outcomemental illnessmodel of autism spectrum disordermouse modelmoviemulti-modalitymultimodalitymurine modelneurophysiologicalneurophysiologynoveloutcome measurementpeople on the autism spectrumpeople with ASDpeople with autismpeople with autism spectrum disorderpre-clinicalpre-clinical studypreclinicalpreclinical studyprogramspsychiatric illnesspsychological disorderrecruitresponseresponse to therapyresponse to treatmentscreeningscreeningssecondary analysissix year oldsix years of ageskill acquisitionskill developmentskillssocialsocial attentionsocial communicationsocial competencesocial competencysocial engagementsocial involvementsocial participationsocial skillsstatistic methodsstatistical analysisstatisticssynergismtherapeutic responsetherapeutically effectivetherapy responsetooltranslationtranslation researchtranslational investigationtreatment responsetreatment responsivenessyoungster
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This career development proposal's overall goal is to prepare the candidate, Alexandra Bey, MD, PhD, for an
independent research career developing and utilizing electrophysiological and behavioral biomarkers for

endophenotyping, stratification, and measuring response to intervention to improve social engagement in autism.

This will be accomplished…

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Electrophysiological biomarkers of social engagement in autism — DUKE UNIVERSITY | UNITED STATES | Sept 2024 | Dev Procure