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electroencephalography and single-unit recordings

Organization UNIVERSITY OF WISCONSIN-MADISONLocation MADISON, UNITED STATESPosted 15 Dec 2020Deadline 30 Nov 2025 โš ๏ธ
NIHUS FederalResearch GrantFY202521+ years oldAbscissionAdultAdult HumanAffectAnimal ModelAnimal Models and Related StudiesAreaAutoregulationBiological MarkersBrainBrain Nervous SystemChemosensitizationChemosensitization/PotentiationChronicCognitiveCognitive DisturbanceCognitive ImpairmentCognitive declineCognitive function abnormalComaComatoseConsciousConsciousnessDataData SetDelta WaveDelta Wave sleepDiseaseDisorderDisturbance in cognitionDoctor of PhilosophyDown-RegulationDrugsDysfunctionEEGElectroencephalogramElectroencephalographyEncephalonEpilepsyEpileptic SeizuresEpilepticsExcisionExtirpationFocal EpilepsyFocal Seizure DisorderFrequenciesFunctional disorderHomeostasisHourHumanImpaired cognitionInjuryInnovative TherapyInvestigatorsLinkLocalization-Related EpilepsyMedicalMedicationMethodsMicroelectrodesMiniaturized ElectrodesMissionModern ManNational Institutes of HealthNerve CellsNerve UnitNervous System DiseasesNervous System DisorderNeural CellNeurocyteNeurologic DisordersNeurological DisordersNeuronsNormal RangeNormal ValuesOperative ProceduresOperative Surgical ProceduresOutcomePartial EpilepsiesPartial Seizure DisorderPatientsPatternPeripheralPh.D.PhDPharmaceutical PreparationsPhysiological HomeostasisPhysiopathologyPopulationPotentiationProceduresPublic HealthRecurrenceRecurrentRefractoryRemovalResearchResearch PersonnelResearchersResolutionRiskSeizure DisorderSeizuresSleepSlow-Wave SleepSurgicalSurgical InterventionsSurgical ProcedureSurgical RemovalSynapsesSynapticTechnical ExpertiseUnited StatesUnited States National Institutes of HealthUniversitiesadulthoodbio-markersbiologic markerbiomarkercognitive dysfunctioncognitive lossdensitydiagnostic biomarkerdiagnostic markerdiagnostic tooldrug/agentepilepsiaepilepsy monitoringepilepsy participantepilepsy patientepilepsy recordingepilepsy subjectepilepsy trackingepilepsy volunteerepileptic monitoringepileptic patientepileptic recordingepileptic subjectepileptiform monitoringepileptiform recordingepileptiform trackingepileptogenicepileptogenic monitoringimprovedimprovement on sleepinjuriesinnovateinnovationinnovativeinsightmodel of animalneural mechanismneurological diseaseneuromechanismneuronalneuroprotectionneuroprotectivenew diagnosticsnew drug treatmentsnew drugsnew pharmacological therapeuticnew therapeutic approachnew therapeutic interventionnew therapeutic strategiesnew therapeuticsnew therapynew therapy approachesnew treatment approachnew treatment strategynext generation diagnosticsnext generation therapeuticsnovelnovel diagnosticsnovel drug treatmentsnovel drugsnovel pharmaco-therapeuticnovel pharmacological therapeuticnovel therapeutic approachnovel therapeutic interventionnovel therapeutic strategiesnovel therapeuticsnovel therapynovel therapy approachpathophysiologypatients with epilepsyrecruitresectionresolutionsseizure detectionseizure monitoringseizure recordingseizure trackingsleep improvementspatial and temporalspatial temporalspatiotemporalsurgerysynapsetechnical skillsvalidation studies

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Description preview

Scientific abstract
Epilepsy is a chronic and debilitating disease, leading to refractory seizures in up to 40% of patients. A

better understanding of the neural mechanisms that cause recurrent seizures could lead to improved

diagnostic markers and new neuroprotective therapies.

My recent research suggests that abnormal slow-wave activity (SWA)โ€ฆ

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