grant

Efficacy of an activities-based locomotor training program in children with cerebral palsy

Organization BAYLOR UNIVERSITYLocation WACO, UNITED STATESPosted 1 Sept 2025Deadline 31 Aug 2028
NIHUS FederalResearch GrantFY20250-11 years old6 year old6 years of ageAcquired brain injuryAddressAffectAgeAssessment instrumentAssessment toolBirthBlood flowBody WeightBrainBrain InjuriesBrain Nervous SystemCNS plasticityCaringCerebral PalsyChildChild YouthChildhoodChildren (0-21)Children with DisabilitiesClassificationClinicalClinical ResearchClinical StudyCross-Over DesignsCross-Over StudiesCrossover DesignCrossover StudiesDataDisabled ChildrenDiseaseDisorderEducation for InterventionEducational InterventionEncephalonEnvironmentEvidence based practiceFutureHandicapped ChildrenHealthHealth CareIndividualInstruction InterventionInternationalInterventionInvestigatorsLifeLightLive BirthLocomotor trainingMeasurementMeasuresMedical RehabilitationMentorsMissionMonitorMotorMotor SkillsMovementMulti-Institutional Clinical TrialMulti-center clinical trialMulti-site clinical trialMulticenter clinical trialMultisite clinical trialNICHDNational Institute of Child Health and Human DevelopmentNervous System DiseasesNervous System DisorderNeurologicNeurologic DisordersNeurologicalNeurological DisordersNeuronal PlasticityOutcomeOutcome MeasureParturitionPh D studentPh D. studentPh. D. studentPh.D studentPh.D. studentPhD studentPhD. studentPhotoradiationPhysiatric ProcedurePhysical Medicine ProcedurePhysical TherapeuticsPhysical therapyPhysiotherapyPlayPopulationPosturePrefrontal CortexProductivityProtocolProtocols documentationQOL improvementRandomizedRegulationRehabilitationRehabilitation therapyResearchResearch DesignResearch PersonnelResearchersSample SizeStructureStudentsStudy TypeSystematicsTechniquesTherapeuticTherapeutic InterventionTimeTrainingTraining InterventionTraining ProgramsUniversitiesWalkingWorld Health Organizationage 6 yearsagedagesbehavior outcomebehavioral outcomebody movementbrain damagebrain-injuredcare as usualcentral nervous system plasticityclinical practiceclinical trainingcomparativecustomized therapycustomized treatmentdecrease disabilitydecrease in disabilitydesigndesigningdetermine efficacydisabilitydisability reductiondoctoral studentefficacy analysisefficacy assessmentefficacy determinationefficacy evaluationefficacy examinationevaluate efficacyexamine efficacyfNIRSfunctional gainfunctional improvementfunctional near infrared spectroscopyfunctional outcomeshemodynamicsimprove functionimprovedimproved functional outcomesimproved motor functionimprovements in QOLimprovements in quality of lifeindividualized clinical decisionindividualized decisionindividualized medicineindividualized patient treatmentindividualized therapeutic strategyindividualized therapyindividualized treatmentinnovateinnovationinnovativeinstructional interventioninternational health organizationintervention therapykidslessen disabilitylocomotor learningmeasurable outcomeminimize disabilitymitigate disabilitymotor abilitymotor function improvementmotor learningmultidisciplinaryneuralneural imagingneural plasticityneuro-imagingneuroimagingneurological diseaseneurological imagingneuroplasticneuroplasticitynew approachesnovel approachesnovel strategiesnovel strategyoutcome measurementpatient specific therapiespatient specific treatmentpediatricpersonalized clinical decisionpersonalized data-driven decisionpersonalized decisionphysical therapistphysiotherapistprimary outcomeprogramsquality of life improvementrandomisationrandomizationrandomly assignedrecruitreduction in disabilityrehab researchrehab strategyrehab therapyrehabilitation researchrehabilitation strategyrehabilitativerehabilitative therapyresponsesix year oldsix years of ageskillsslow disabilitystandard of carestudy designtailored medical treatmenttailored therapytailored treatmenttooltraining opportunitytreadmill trainingtreatment as usualundergradundergraduateundergraduate studentunique treatmentusual carewalking pacewalking speedyoungster
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PROJECT SUMMARY
Cerebral Palsy (CP) is a common lifelong neurological disorder affecting movement and posture, requiring

ongoing physical therapy to achieve functional gains. This project aims to evaluate the efficacy of an Activities-

Based Locomotor Training (AB-LT) program for young non-ambulatory children with CP, addressing the gap in

current…

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