grant
Dynamics of hematopoietic differentiation
Organization DIVISION OF BASIC SCIENCES - NCILocation UNITED STATES
NIHUS FederalResearch GrantFY2025Aberrant TissueAbnormal CellAddressAutoimmuneAutoregulationBehaviorBiologic PhenomenaBiological PhenomenaBloodBlood Cell CountBlood Cell NumberBlood Reticuloendothelial SystemBlood erythrocyteBody TissuesBone MarrowBone Marrow Reticuloendothelial SystemCancer BurdenCell BodyCell Communication and SignalingCell Growth in NumberCell MultiplicationCell ProliferationCell SignalingCellsCellular ProliferationChoristomaCommentCommentaryDiseaseDisorderEctopic TissueEditorial CommentErythrocytesErythrocyticExhibitsFrequenciesGoalsHematopoiesisHematopoietic Cellular Control MechanismsHeterotopic TissueHomeostasisImmune systemImmunotherapeutic agentInflammatoryIntracellular Communication and SignalingLymphoidLymphoid CellManuscriptsMarrow erythrocyteMeasurementModelingMyelogenousMyeloidMyeloid CellsNational Cancer BurdenOncogenesisOrganOrganismPaperPatientsPhysiological HomeostasisProcessProliferatingPublished CommentRed Blood CellsRed CellResearchRestSignal TransductionSignal Transduction SystemsSignalingSpleenSpleen Reticuloendothelial SystemTextbooksTissuesVariantVariationVascular blood supplyViewpointbiological signal transductionblood cell formationblood corpusclesblood supplycancer immunologycell typehematopoietic differentiationimmune drugsimmune-based therapeuticsimmunologic therapeuticsimmunotherapeuticsimmunotherapy agentinterestleukemialiving systemneoplasm immunologystemtumor immunologytumorigenesisvascular supply
Description preview
We finalized a manuscript detailing our most recent experimental results and modeling effort. This paper was submitted to biorxiv and is being adjusted to address reviewers' comments. Homeostatic hematopoiesis is a dynamical process, characterized by large variations of cell frequencies, cell proliferation rates and extensive…
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