grant

Drug concentration measurement for HIV prevention targets: toward a population-based HIV impact assessment (PHIA) for PrEP

Organization NEW YORK UNIVERSITY SCHOOL OF MEDICINELocation NEW YORK, UNITED STATESPosted 15 Feb 2024Deadline 31 Dec 2028
NIHUS FederalResearch GrantFY202521+ years oldAIDS VirusAIDS preventionAIDS testAIDS/HIVAIDS/HIV testAchievementAchievement AttainmentAcquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome VirusAdherenceAdoptedAdultAdult HumanAdvocateAfrica South of the SaharaAgeAnti-viral AgentsAutomobile DrivingBehavioralBioethicsBiomedical EthicsBlood PlasmaBlood SampleBlood specimenCause of DeathConcentration measurementCountryDataDevelopmentDiagnosisDrugsEpidemicFemale AdolescentsFormulationGeneral PopulationGeneral PublicGoalsGovernmentGuidelinesHIVHIV InfectionsHIV PreventionHIV SeronegativitiesHIV SeronegativityHIV negativeHIV riskHIV testHIV-1 testHIV-2 testHIV/AIDSHIV/AIDS preventionHTLV-III InfectionsHTLV-III SeronegativitiesHTLV-III SeronegativityHTLV-III-LAV InfectionsHeterosexualsHomeHuman Immunodeficiency VirusesHuman T-Lymphotropic Virus Type III InfectionsHuman immunodeficiency virus testIncidenceIndividualInternational AgenciesInterruptionInvestigatorsKenyaKidney Function TestsLAV-HTLV-IIILicensureLymphadenopathy-Associated VirusMSMMan who have sex with ManMapsMeasurementMeasuresMedicationMethodsModelingMonitorObservation researchObservation studyObservational StudyObservational researchOralParticipantPersonsPharmaceutical PreparationsPlacebosPlasmaPlasma SerumPolicy MakerPopulationPopulation GroupPopulation SurveillancePrEPPublic Health SurveillanceReportingResearchResearch PersonnelResearchersReticuloendothelial System, Serum, PlasmaRiskRisk BehaviorsRisk ReductionRisky BehaviorScientific Advances and AccomplishmentsScientistSeriesSham TreatmentSouth AfricaStudy modelsSub-Saharan AfricaSubsaharan AfricaSurvey InstrumentSurveysSustainable DevelopmentTimeTransmissionViralViral BurdenViral LoadViral Load resultVirus-HIVWomanWorld Health Organizationactive controladolescent girladulthoodagesanti-viral compoundanti-viral drugsanti-viral medicationanti-viral therapeuticanti-viralsat risk behaviorcivil societycohortcommunity advisory boardcommunity advisory committeecommunity advisory panelcomparativecost effectivedesigndesigningdevelopmentaldrivingdrug/agentexperiencehomesimplementation studyinnovateinnovationinnovativeinterestmarkov modelmeetingmeetingsmen having sex with menmen who have sex with menmen who have sex with other menmethods to study multiple-level influencesmortalitymulti-level analysismulti-level modelmultilevel analysismultilevel modelmultilevel modelingpharmacologicpopulation basedpre-exposure prophylaxispreferenceprogramsreduce riskreduce risksreduce that riskreduce the riskreduce these risksreduces riskreduces the riskreducing riskreducing the riskrisk-reducingscale upscientific accomplishmentsscientific advancesself testingseroconversionsham therapysocial stigmastigmatransmission processyoung woman
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Description preview

Sub-Saharan Africa (SSA) is home to two-thirds of all people living with HIV (PLHIV). Widely-adopted targets
such as “95-95-95” (diagnosing ≥95% of PLHIV, treating ≥95% of those diagnosed, and achieving viral load

suppression in ≥95% of those on treatment) have fueled tremendous progress in access and effective use of

HIV treatment, with…

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