grant

DNA methylation markers to predict treatment success of biologicals in Crohn’s disease

Organization UKRILocation United Kingdom
UKRIUK ResearchGrantActive
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Description preview

Monoclonal antibodies have become a mainstay of therapy in common immune-mediated diseases (IMID) including Crohn’s disease (CD), rheumatoid arthritis (RA), and psoriasis (PsO). Current therapeutics include antibodies (“biologicals”) targeting inflammatory proteins such as Tumor Necrosis Factor (adalimumab), leukocyte trafficking (vedolizumab), or…

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DNA methylation markers to predict treatment success of biologicals in Crohn’s disease — UKRI | United Kingdom | Dev Procure