grant

Discovery Science Collaborative for CKDu

Organization STANFORD UNIVERSITYLocation STANFORD, UNITED STATESPosted 25 Aug 2021Deadline 30 Jun 2028
NIHUS FederalResearch GrantFY2025AcuteAcute Kidney FailureAcute Kidney InsufficiencyAcute Renal FailureAcute Renal InsufficiencyAffectAfricaAgricultural ChemicalsAgricultural WorkersAgrochemicalsAssayBioassayBioinformaticsBiological AssayBiological MarkersBiopsyBlood SerumCausalityCell BodyCellsCentral AmericaCentral AsiaCeylonCharacteristicsChronicChronic Kidney FailureChronic Renal DiseaseChronic Renal FailureClinicalCollaborationsCommunitiesCountryDataData BasesData Coordinating CenterData Coordination CenterDatabasesDeveloping CountriesDeveloping NationsDiabetes MellitusDiseaseDisease ProgressionDisorderDysfunctionEast AsiaEastern AsiaElectrolytesEnvironmental FactorEnvironmental Risk FactorEnvironmental ToxinEpidemiologyEtiologyEvaluationFar EastFoundationsFunctional disorderFundingGenetic PredispositionGenetic Predisposition to DiseaseGenetic SusceptibilityGenetic propensityGenetic studyGenomicsGeographyGlomerular Filtration RateGoalsHeat StressHeterogeneityHistoryHypertensionIndiaIndividualInflammatory InfiltrateInfrastructureInherited PredispositionInherited SusceptibilityInitiation FactorsInjuryInjury to KidneyInstitutionInternationalInvestigative TechnicsInvestigative TechniquesKidneyKidney DiseasesKidney Urinary SystemLeadershipLess-Developed CountriesLess-Developed NationsManualsMass Photometry/Spectrum AnalysisMass SpectrometryMass SpectroscopyMass SpectrumMass Spectrum AnalysesMass Spectrum AnalysisMetabolic PathwayMethodsMolecularNIDDKNational Institute of Diabetes and Digestive and Kidney DiseasesNational Institutes of HealthNatural HistoryNephrologyNephropathyParticipantPathogenesisPathologyPatientsPeptide Initiation FactorsPersonsPhysiologyPhysiopathologyPopulationPredispositionProteinsProteomicsRecording of previous eventsRegulationRenal DiseaseRenal functionReportingResearchResearch ResourcesResourcesRisk FactorsRoleSamplingScienceSerumSingle cell seqSiteSouth AmericaSri LankaSusceptibilityTechnologyThird-World CountriesThird-World NationsTimeToxic Environmental AgentsToxic Environmental SubstancesTranslation Initiation FactorTranslational Initiation FactorTubularTubular formationUnder-Developed CountriesUnder-Developed NationsUnited States National Institutes of HealthVascular Hypertensive DiseaseVascular Hypertensive DisorderWorkacute kidney injuryagricultural communityagriculture workerbio-markersbiobankbiologic markerbiomarkerbiomarker developmentbiomarker identificationbiorepositorycausationchronic kidney diseaseclinical phenotypeco-morbidco-morbiditycommunity researchcomorbiditydata basedata integrationdesigndesigningdeveloping countrydeveloping nationdiabetesdiagnostic approachdiagnostic strategydigital pathologydisease causationemerging pathogenenvironmental riskenvironmental toxicantepidemiologicepidemiologicalexperienceexperimentexperimental researchexperimental studyexperimentsflexibilityflexiblegenetic etiologygenetic mechanism of diseasegenetic vulnerabilitygenetically predisposedhigh blood pressurehistorieshyperpiesiahyperpiesishypertensive diseasehypertensive disorderidentification of biomarkersidentification of new biomarkersinjurieskidney biopsykidney disorderkidney functionkidney injurymachine learned algorithmmachine learning algorithmmachine learning based algorithmmarker identificationmetabolism measurementmetabolomicsmetabonomicsmolecular pathologynew pathogennon-invasive diagnosisnon-invasive diagnosticnoninvasive diagnosisnoninvasive diagnosticnovel imaging technologynovel pathogenoutcome predictionpathogenpathophysiologyrenalrenal biopsyrenal disorderrenal injurysingle cell next generation sequencingsingle cell sequencingsocial roletooltranscriptomicsurinarywork groupworking group
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PROJECT SUMMARY / ABSTRACT
The overall goal of the Discovery Science Collaborative for CKDu Renal Science Core is to bring the best

investigative methods and scientific technology to the problem of CKDu. We will work closely with Field

Epidemiology Sites, the Scientific Data Coordinating Center, NIDDK Leadership, the External Oversight

Committee,…

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Discovery Science Collaborative for CKDu — STANFORD UNIVERSITY | UNITED STATES | Aug 2021 | Dev Procure