grant
Discovery and mechanisms of biosynthetic enzymes
Organization UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAHLocation SALT LAKE CITY, UNITED STATESPosted 1 May 2018Deadline 31 Aug 2028
NIHUS FederalResearch GrantFY2025AnabolismBiochemicalBiologicalClinicComplexDevelopmentDiseaseDisorderEnvironmentEnzyme GeneEnzymesGleanGoalsIntermediary MetabolismMetabolic ProcessesMetabolismMolecularNatural ProductsNucleic AcidsOrganismPathway interactionsPeptidesPhysiologyProcessRibosomesRoleStructure-Activity RelationshipTechniquesbiologicbiosynthesischemical structure functiondevelopmentalenzyme mechanisminsightliving systemnaturally occurring productnovelpathwaysecondary metabolitesmall moleculesocial rolestructure function relationshiptherapeutic agent developmenttherapeutic development
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PROJECT SUMMARY
Biosynthetic pathways are rich in enzymatic transformations that produce structurally
diverse natural products, such as secondary metabolites, modified nucleic acids, and
modified peptides. Discovering and understanding the molecular basis for these
transformations underpins efforts towards development of deep insights into factors…
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