grant
Development of Therapeutic Products for Antibiotic Resistant Bacteria
NIHUS FederalResearch GrantFY2025Advanced DevelopmentBacteria resistanceBacteria resistantBacterial Antibiotic ResistanceBacterial Drug ResistanceBacterial resistantChemistryClinical assessmentsCombating Antibiotic Resistant BacteriaDevelopment and ResearchEmerging Communicable DiseasesEmerging Infectious DiseasesIND FilingIND applicationIND packageIND submissionInvestigational New Drug ApplicationP aeruginosaP. aeruginosaPseudomonas aeruginosaPseudomonas pyocyaneaR & DR&DResearch SupportTherapeuticanti-bacterial drug resistanceanti-bacterial drug resistantanti-bacterial resistanceanti-bacterial resistantantibiotic resistant bacteriabacterial antibiotic resistantbacterial resistancebacterial resistance to antibioticbiodefensecandidate selectiondetermine efficacyefficacy analysisefficacy assessmentefficacy determinationefficacy evaluationefficacy examinationevaluate efficacyexamine efficacylead optimizationmanufacturepathogenpre-clinicalpreclinicalproduct developmentresearch and developmentresistance to Bacteriaresistance to Bacterialresistance to anti-bacterialresistant to Bacteriaresistant to Bacterialresistant to anti-bacterialsafety assessmenttherapeutic agent developmenttherapeutic candidatetherapeutic development
Full Description
To support the advanced development of candidate therapeutics for biodefense pathogens or emerging infectious diseases. The supported research and development activities will progress the therapeutic product development and may include lead optimization, candidate selection, preclinical and IND enabling studies, Chemistry, Manufacturing, and Controls (CMC), IND submission, clinical safety and efficacy assessment.
Grant Number: 75N93020C00019-P00014-9999-1
NIH Institute/Center: NIH
Principal Investigator: TERRY BOWLIN
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