grant

Development of the Connectome II MRI Scanner

NIHUS FederalResearch GrantFY2025ArchitectureAreaArtifactsAtlasesAxonBRAIN initiativeBiophysicsBody TissuesBrainBrain Nervous SystemBrain Research through Advancing Innovative Neurotechnologies initiativeBrain imagingCallithrixCell Communication and SignalingCell SignalingClinicalClinical EvaluationClinical TestingCommunitiesCustomDWI (diffusion weighted imaging)DWI-MRIDataDevelopmentDevelopment and ResearchDiameterDiffusionDiffusion MRIDiffusion Magnetic Resonance ImagingDiffusion Weighted MRIDiffusion weighted imagingDiffusion-weighted Magnetic Resonance ImagingDimensionsEncephalonEngineering / ArchitectureEnsureExperimental DesignsFamilyFractalsFundingGoalsGrantHapaleHeterogeneityHumanHydrogen OxideImageImaging DeviceImaging InstrumentImaging ToolInfrastructureIntracellular Communication and SignalingInvestigatorsLengthMR ImagingMR TomographyMRIMRIsMacacaMacaqueMagnetic Resonance ElastographyMagnetic Resonance ImagingMarmosetsMathMath ModelsMathematicsMeasuresMedical Imaging, Magnetic Resonance / Nuclear Magnetic ResonanceMethodologyMethodsMicroscopicModelingModern ManMorphologic artifactsMorphologyNMR ImagingNMR TomographyNational Institutes of HealthNoiseNuclear Magnetic Resonance ImagingPerformancePhysiciansPhysiologic pulsePulseR & DR&DResearch PersonnelResearchersResolutionRoleScanningShort-Tusked MarmosetSideSignal TransductionSignal Transduction SystemsSignalingStructureTestingTimeTissuesTranslatingUnited States National Institutes of HealthWaterZeugmatographybiological signal transductionbiophysical foundationbiophysical principlesbiophysical sciencesbrain visualizationclinical applicabilityclinical applicationclinical implementationclinical testclinical translationclinically translatableconnectomecustomsdMRIdevelopmentaldiffuseddiffusesdiffusingdiffusion tensor imagingdiffusionshistologic imagehistological imageimage processingimage-based methodimagingimaging methodimaging modalityin vivoinventionmagnetic fieldmathematic modelmathematical modelmathematical modelingmigrationnovelphysical modelprocessing speedprototyperesearch and developmentresearch clinical testingresolutionssocial rolevolunteerwater diffusion
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We are continuing to develop novel diffusion MRI-based pulse sequence, acquisition, and signal modeling frameworks to enable us to "see" or detect fine-scale structures in the living human brain that are three orders of magnitude smaller than the underlying MRI voxel size, and which are currently invisible using clinical MRI scanners.…

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Development of the Connectome II MRI Scanner — EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOP | Dev Procure