grant

DEVELOPMENT OF PAN-FILOVIRUS THERAPEUTICS

Organization MICROBIOTIX, INCLocation WORCESTER, UNITED STATESPosted 1 Nov 2022Deadline 1 Mar 2027
NIHUS FederalResearch GrantFY2025Advanced DevelopmentChemistryClinicalDevelopmentDevelopment and ResearchEBOVEbola virusEbola-like VirusesFiloviridaeFilovirusOrthoebolavirusPathway interactionsR & DR&DTherapeuticViralVirusanti-viral developmentanti-viral drug developmentanti-viral therapeutic developmentanti-viral therapy developmentantiviral developmentantiviral drug developmentantiviral therapeutic developmentantiviral therapy developmentdetermine efficacydeveloping anti-viral agentdeveloping anti-viral drugdeveloping anti-viral therapeuticdeveloping anti-viral therapydeveloping antiviral agentdeveloping antiviral drugdeveloping antiviral therapeuticdeveloping antiviral therapydevelopmentalefficacy analysisefficacy assessmentefficacy determinationefficacy evaluationefficacy examinationevaluate efficacyexamine efficacymanufacturepandemicpandemic diseasepathwaypre-clinicalpreclinicalproduct developmentprogramsresearch and developmentsafety assessmenttherapeutic candidate
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Full Description

To support the advanced development of a promising candidate therapeutic for a virus under the Antiviral Program for Pandemics. The research and development activities to be supported will allow the candidate therapeutic product to progress through the product development pathway, and include preclinical and IND enabling development activities, chemistry optimization/development, GMP manufacturing, and clinical safety and efficacy assessment.

Grant Number: 75N93023C00001-P00003-9999-1
NIH Institute/Center: NIH
Principal Investigator: TERRY BOWLIN

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