grant
Development of integrated OCT/US/PAT system for intravascular Imaging
Organization UNIVERSITY OF CALIFORNIA-IRVINELocation IRVINE, UNITED STATESPosted 15 Aug 2025Deadline 31 May 2029
NIHUS FederalResearch GrantFY202521+ years oldASCVDAcute Coronary EventAddressAdultAdult HumanAffectAreaArterial Fatty StreakArteriesArtifactsAtheromaAtheromatousAtheromatous degenerationAtheromatous plaqueAtherosclerosisAtherosclerotic Cardiovascular DiseaseBasic ResearchBasic ScienceBenchmarkingBest Practice AnalysisBiometricsBiometryBiostatisticsBirefractionBirefringenceBody TissuesCardiologyCardiovascular DiseasesCathetersCessation of lifeChemicalsClinicalClinical ManagementCollaborationsCoronary ArteriosclerosisCoronary Artery DiseaseCoronary Artery DisorderCoronary AtherosclerosisDeathDetectionDevelopmentDiagnosisDisease ProgressionDomestic RabbitDoppler OCTDouble RefractionEarly DiagnosisElementsEngineeringEpidemiologyEvaluationEventFluorescenceHeartImageImaging ProceduresImaging TechnicsImaging TechniquesInstitutionInterventionInvestigatorsLaser ElectromagneticLaser RadiationLasersLengthLesionLightMechanicsMedical DeviceMedical DirectorsModalityMolecularMonitorMorphologic artifactsMorphologyMotionMovementMultimodal ImagingOCT TomographyOptical Coherence TomographyOryctolagus cuniculusOutcomePathogenesisPathologyPenetrationPhotoradiationPhysician ExecutivesPhysiciansPhysiologicPhysiologic pulsePhysiologicalPlaque InstabilityPlaque RuptureProceduresPulseRabbitsRabbits MammalsRadiation exposureResearchResearch PersonnelResearchersResolutionRiskRoentgen RaysScientistSourceSpeedSystemTechniquesTechnologyTherapeutic InterventionTimeTissuesUltrasonic TransducerUltrasound transducerVisualizationX-RadiationX-Ray RadiationX-rayXrayabdominal aortaadulthoodatheromatosisatherosclerosis plaqueatherosclerotic coronary diseaseatherosclerotic diseaseatherosclerotic lesionsatherosclerotic plaqueatherosclerotic plaque ruptureatherosclerotic vascular diseasebenchmarkbody movementcardiovascular disorderclinical translationclinically translatablecoronary arterial diseasecostdesigndesign and constructdesign and constructiondesigningdevelopmentalearly detectionepidemiologicepidemiologicalhigh riskhuman errorimage guided interventionimagingimaging probeimaging systemimprovedin vivoinstrumentintervention therapymechanicmechanicalmulti-modal imagingmulti-modalitymulti-modality imagingmultimodalitymultimodality imagingnanosecondoptical Doppler tomographyoptical coherence Doppler tomographyoptoacoustic tomographyphotoacoustic tomographypig modelpiglet modelplaque vulnerabilityplaques in atherosclerosisporcine modelresolutionssafe patientswine modeltherapeutic effectivenesstissue maptissue mappingtoolultrasoundunstable plaque
Description preview
PROJECT SUMMARY
Coronary artery disease (CAD) is the most prevalent cardiovascular disease, impacting over 18 million
adults and causing more than 350,000 deaths annually in recent years. Acute coronary events are primarily
caused by ruptured atherosclerotic plaques, emphasizing the need for early detection and accurate identification
of plaque…
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