grant
Development of a Novel Therapeutic for Melioidosis
Organization AN2 THERAPEUTICS, INC.Location MENLO PARK, UNITED STATESPosted 20 Sept 2022Deadline 30 Sept 2026
NIHUS FederalResearch GrantFY2025Advanced DevelopmentB pseudomalleiB. pseudomalleiBurkholderia pseudomalleiChemistryClinical assessmentsDevelopmentDevelopment and ResearchEmerging Communicable DiseasesEmerging Infectious DiseasesIND FilingIND applicationIND packageIND submissionInvestigational New Drug ApplicationMelioidosisP pseudomalleiP. pseudomalleiPseudomonas pseudomalleiR & DR&DResearch SupportTherapeuticbiodefensecandidate selectiondetermine efficacydevelopmentalefficacy analysisefficacy assessmentefficacy determinationefficacy evaluationefficacy examinationevaluate efficacyexamine efficacylead optimizationmanufacturenew drug treatmentsnew drugsnew pharmacological therapeuticnew therapeuticsnew therapynext generation therapeuticsnovel drug treatmentsnovel drugsnovel pharmaco-therapeuticnovel pharmacological therapeuticnovel therapeuticsnovel therapypathogenpre-clinicalpreclinicalproduct developmentresearch and developmentsafety assessmenttherapeutic agent developmenttherapeutic candidatetherapeutic development
Full Description
To support the advanced development of candidate therapeutics for biodefense pathogens or emerging infectious diseases. The supported research and development activities will progress the therapeutic product development and may include lead optimization, candidate selection, preclinical and IND enabling studies, Chemistry, Manufacturing, and Controls (CMC), IND submission, clinical safety and efficacy assessment.
Grant Number: 75N93022C00059-P00008-9999-1
NIH Institute/Center: NIH
Principal Investigator: M.R.K. (DICKON) ALLEY
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