grant

Developing AI-measures of Pedestrian Environment Features for Physical Activity and Cancer Prevention in Rural Communities

Organization ARIZONA STATE UNIVERSITY-TEMPE CAMPUSLocation SCOTTSDALE, UNITED STATESPosted 1 Mar 2025Deadline 28 Feb 2027
NIHUS FederalResearch GrantFY202621+ years oldAI systemAddressAdultAdult HumanAmerican Cancer SocietyAreaArtificial IntelligenceBuffersCancer Death RatesCancersCell Communication and SignalingCell SignalingComputer ReasoningDataDeath RateDisparateDisparitiesDisparityEconomic IncomeEconomical IncomeEnvironmentEthnic OriginEthnicityExhibitsFundingGeographic AreaGeographic LocationsGeographic RegionGeographical LocationGeographyGreen spaceHealthHealth CareHumanIlluminationImageImpoverishedIncidenceIncomeInternationalInterventionIntracellular Communication and SignalingLightingLinkLocalesLocationLow incomeMachine IntelligenceMalignant NeoplasmsMalignant TumorMeasuresMethodologyModern ManNCI OrganizationNational Cancer InstituteNeighborhoodsPatient Self-ReportPersonsPhysical activityPoliciesPovertyPreventative strategyPrevention strategyPreventive strategyQuestionnairesRaceRacesRampRecommendationResearchResearch ResourcesResourcesRisk FactorsRoleRuralRural CommunityRural PopulationRural groupRural peopleSafetySamplingScreening for cancerSelf-ReportSignal TransductionSignal Transduction SystemsSignalingSpeedStandardizationTechnologyTestingTrainingUnited StatesUrban PopulationWalkingWorkZebraadulthoodage groupbiological signal transductioncancer disparitycancer health disparitycancer mortality ratecancer preventioncancer related death ratecancer related mortality ratecancer riskcancer specific mortality ratecancer-related health disparitycomputer generatedcostcost effectivedeep learningdeep learning methoddeep learning strategydensitydisparities in racedisparity due to racedisparity in cancerdisparity in ethnicearly cancer detectionenvironmental interventionethnic based disparityethnic disadvantageethnic disparityethnic diversityethnic inequalityethnic inequityethnically diverseethnicity disparityexperiencegeographic disadvantagegeographic disparitygeographic inequalitygeographic inequitygeographic location disparitygeographic sitegreenspacehigh riskimagingimprovedincomesinequality due to raceinequity due to raceinnovateinnovationinnovativelack of physical activityland uselearning classifiermachine learned algorithmmachine learning algorithmmachine learning based algorithmmalignancymid lifemid-lifemiddle agemiddle agedmidlifemortalitymortality rateneoplasm/cancerold agephysical inactivitypreventpreventingrace based disparityrace based inequalityrace based inequityrace disparityrace related disparityrace related inequalityrace related inequityracialracial backgroundracial disparityracial diversityracial inequalityracial inequityracial originracially diverseracially unequalrural arearural dwellersrural environmentrural individualrural locationrural regionrural residentscale upscreening cancer patientssexsocial cohesionsocial rolesocio-economicsocio-economicallysocioeconomicallysocioeconomicssuburbsuburbansuburbiatoolurban areaurban groupurban individualurban locationurban peopleurban regionvirtual humanwalkabilitywalkable
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Full Description

7. Project Summary/Abstract
Residents of rural areas often exhibit lower rates of physical activity (PA), correlating to elevated cancer

incidence and mortality rates compared to urban dwellers. The lack of PA resources significantly contributes to

the lower rates of PA observed among racially and ethnically diverse and lower-income rural populations. A

major obstacle to addressing urban-rural PA and cancer disparities is an insufficient understanding of the

neighborhood environment—specifically, the pedestrian environment features that inhibit or promote PA—

which can be cost-effectively modified. Existing, publicly available pedestrian environment measures assess

macroscale walkability features (e.g., land use mix, street intersection density) that are costly and infeasible to

improve in rural areas. While smaller-scale research has identified more affordable, microscale Pedestrian

Environment Features (PEFs) (e.g., sidewalks, crosswalks, lighting), person-led, microscale audits of PEFs

show limited feasibility across expansive rural geographies. Machine learning algorithms have been developed

using data from urban and suburban areas to audit microscale PEFs, but these can introduce bias when

scaled up for use across expansive rural areas to study their relationship with PA. Addressing urban-rural

cancer disparities necessitates assessing the association between microscale PEFs and PA in both urban and

rural areas of the US. Therefore, we propose three specific aims: 1) further validate existing machine learning

algorithms to assess 9 microscale PEFs (sidewalks, sidewalk buffers, curb ramps, zebra and line crosswalks,

walk signals, bike symbols, benches, and lighting) for rural areas, 2) test the relationship between rural

microscale PEFs and middle to older age adult PA, and 3) identify disparities in microscale PEFs by income

levels, racial and ethnic composition, & geographic location across the US. We will retrain and leverage

existing deep learning classifiers developed as part of preliminary work funded by the National Cancer Institute

to assess urban and suburban microscale PEFs, to create classifiers that generalize and perform well in rural

areas. We will validate these microscale PEF classifiers with human virtual audits and examine their

relationship with PA among middle and older age adults, given this age group is at high risk for physical

inactivity. We hypothesize that greater rural PEFs will be associated with greater minutes per week of total PA

and walking, as measured by the International Physical Activity Questionnaire, after adjusting for covariates.

Finally, we will explore income, racial, ethnic, and regional disparities in rural microscale PEFs across the US

where policy or environmental intervention may be necessary. This project aims to validate a new scalable tool

for identifying rural PEFs and uncovering potential environmental and health-related disparities in diverse rural

locales across the US. Results will inform larger-scale research that uses AI-measured PEF assessments to

address physical inactivity and cancer-related health disparities. In turn, existing cancer prevention and PA

promotion initiatives can intervene on lower-cost and modifiable neighborhood environment features.

Grant Number: 5R21CA293976-02
NIH Institute/Center: NIH

Principal Investigator: Marc Adams

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