grant
Determining the Contributions of Four AARDoC Functional Domains to the Etiology of Heavy Drinking and AUD Symptoms: A Prospective, Multimodal Approach
Organization UNIVERSITY OF IOWALocation IOWA CITY, UNITED STATESPosted 1 Sept 2023Deadline 31 Aug 2028
NIHUS FederalResearch GrantFY202512-20 years oldAccelerationAccountingAdolescenceAdolescentAdolescent YouthAffectAgeAlcohol DrinkingAlcohol consumptionAlcohol dependenceAnxietyBehavior-Related DisorderBehavior-Related ProblemBehavioralBionomicsCausalityConsumptionData CollectionData SetDevelopmentDiagnosisDisinhibitionEcologyEnrollmentEtOH drinkingEtOH useEtiologyFailureFemaleGoalsHeavy DrinkingHeterogeneityImpairmentIndividualIndividual DifferencesInterventionIntervention StrategiesInvestigatorsKnowledgeLifestyle-Related DisorderLifestyle-Related ProblemLifestyle-related conditionLinkMapsMeasuresModalityModelingOutcomeParticipantPatient Self-ReportPatternPersonsPhenotypePlayProcessProspective StudiesRDoCResearchResearch Domain CriteriaResearch PersonnelResearchersRewardsRiskRoleSamplingSelf-ReportSeveritiesShapesSocial EnvironmentSuggestionSymptomsTestingTimeTypologyWorkaddictionaddictive disorderadolescence (12-20)agesalcohol addictionalcohol dependencyalcohol dependentalcohol effectalcohol exposedalcohol exposurealcohol ingestionalcohol intakealcohol involvementalcohol product usealcohol usealcohol use disorderalcoholic beverage consumptionalcoholic drink intakecausationcognitive controlcohortdata structuredesigndesigningdevelopmentaldisease causationdisease classificationdisorder classificationdrink heavilydrinkingearly adulthoodemerging adultemerging adulthoodenrollethanol consumptionethanol drinkingethanol effectethanol exposedethanol exposureethanol ingestionethanol intakeethanol product useethanol useethanol use disorderexcessive alcohol consumptionexcessive alcohol ingestionexcessive alcohol intakeexcessive drinkingexcessive ethanol ingestionexposed to alcoholexposed to ethanolexposure to alcoholexposure to ethanolextreme drinkingheavy alcohol useincentive salienceindexingindividualized preventioninvolvement with alcoholjuvenilejuvenile humanlongitudinal designlongitudinal experimental designlongitudinal research designlongitudinal study designmulti-modalitymultimodalityneural adaptationneuroadaptationneurobehavioralneurophysiologicalneurophysiologynosologypersonalization of treatmentpersonalized health interventionpersonalized interventionpersonalized medicinepersonalized preventionpersonalized therapypersonalized treatmentprecision interventionsprecision preventionprospectivepsychologicpsychologicalsocialsocial climatesocial contextsocial rolesocioenvironmentsocioenvironmentalsymptom clustertheoriestreatment strategy♀
Description preview
PROJECT SUMMARY / ABSTRACT
Alcohol use disorder (AUD) is highly heterogeneous in that its symptoms are highly varied and, often, non-
overlapping across individuals. In theory, this phenotypic heterogeneity reflects the influence of multiple
underlying causes, or etiologic mechanisms. This etiologic complexity makes AUD treatment very challenging;…
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