grant
Definitive Evaluation of Gastric Dysrhythmia as a Disease Mechanism by a Novel Body Surface Gastric Mapping Technique
Organization UNIVERSITY OF LOUISVILLELocation LOUISVILLE, UNITED STATESPosted 15 Jul 2024Deadline 30 Apr 2028
NIHUS FederalResearch GrantFY202521+ years oldAcid RefluxAddressAdultAdult HumanAffectAntralAnxietyBiological MarkersBiomedical EngineeringBluetoothBody SurfaceBody TissuesCell Communication and SignalingCell SignalingChronicClinicalClinical ResearchClinical StudyConsensusCoupledCustomCutaneousDataDevicesDiagnosisDiagnosticDiagnostic testsDiseaseDisorderDysfunctionDyspepsiaEconomic BurdenEconomicsElectrical ImpedanceElectrodesElectronicsElectrophysiologyElectrophysiology (science)Esophageal RefluxEvaluationEventFrequenciesFunctional disorderFutureGERDGamma Camera ImagingGastric EmptyingGastric StasisGastro-oesophageal RefluxGastroesophageal RefluxGastroesophageal reflux diseaseGastroparesisGuidelinesHealthImpairmentImpedanceIndigestionInterventionIntracellular Communication and SignalingInvestigatorsJournalsLinkMagazineMapsMental DepressionMethodsMotilityNatural HistoryNausea and VomitingNeurophysiology / ElectrophysiologyOutcomePathologyPatient SelectionPatientsPatternPhenotypePhysiologyPhysiopathologyPopulationPrevalencePublishingQOLQuality of lifeRadioisotope ScanningRadionuclide ImagingRefluxResearch PersonnelResearchersRoleRomeScintigraphySelection for TreatmentsSeriesSeveritiesSignal TransductionSignal Transduction SystemsSignalingSkinStomachSubgroupSymptomsSyndromeTechniquesTechnologyTestingTissuesTranslatingTranslationsValidationadulthoodanalysis pipelinebio-engineeredbio-engineersbio-markersbioelectricbioelectricitybioengineeringbiologic markerbiological engineeringbiological signal transductionbiomarkerclinical careclinical diagnosticsclinical significanceclinical trial readinessclinically significantcohortcustomsdelayed gastric emptyingdepressiondiagnostic approachdiagnostic platformdiagnostic strategydiagnostic systemdiagnostic tooldisease phenotypeeconomicelectric impedanceelectronicelectronic deviceelectrophysiologicalflexibilityflexiblegastricgut to brain axisgut-brain axisgut-brain communicationgut-brain interactionsgut-brain relationshipgut-brain signalinginnovateinnovationinnovativeinsightmedical diagnosticneuromuscularnew diagnosticsnew drug targetnew druggable targetnew markernew pharmacotherapy targetnew therapeutic targetnew therapy targetnext generation diagnosticsnon-invasive diagnosisnon-invasive diagnosticnoninvasive diagnosisnoninvasive diagnosticnovelnovel biomarkernovel diagnosticsnovel drug targetnovel druggable targetnovel markernovel pharmacotherapy targetnovel therapeutic targetnovel therapy targetpathophysiologypatient subclasspatient subclusterpatient subgroupspatient subpopulationspatient subsetspatient subtypespre-clinical developmentpreclinical developmentprogramsradionuclide imaging/scanningradionuclide scanningresponseresponse biomarkerresponse markersselection of treatmentsocial rolestomach emptyingtherapy selectiontooltranslationtranslational studytreatment selectionvalidations
Description preview
Functional dyspepsia and chronic nausea and vomiting syndromes affect >10% of the population, inducing a
vast burden of ill-health and economic harm. Yet despite their enormous impact, these diseases remain poorly
understood, with few objective diagnostic tests available to subtype patients and direct therapies. There is a
pressing need for new…
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