grant

Decoding Microbial Diversity in the Human Gut Microbiome

Organization PENNSYLVANIA STATE UNIVERSITY, THELocation UNIVERSITY PARK, UNITED STATESPosted 1 Aug 2023Deadline 31 May 2028
NIHUS FederalResearch GrantFY2025AddressAffectAlimentary CanalAnimal ModelAnimal Models and Related StudiesAnti-Bacterial AgentsAnti-malarialsAutoimmune DiseasesBig DataBigDataBile AcidsBiologicalCancersCommunicable DiseasesCommunitiesComplexComputational BiologyCoupledDataDigestive TractDrugsEquilibriumFamilyGI TractGI microbiomeGastrointestinal TractGastrointestinal tract structureGenetic DiversityGenetic VariationGenomeGenotypeGnotobioticGnotobioticsGoalsHealthHigh-Throughput Nucleotide SequencingHigh-Throughput SequencingHumanHuman MicrobiomeInfectious DiseasesInfectious DisorderLibrariesMalignant NeoplasmsMalignant TumorMedicationMedicineMetabolicMetabolic PathwayMicrobeMicrobiomicsMissionModern ManOral AdministrationOral Drug AdministrationOrganismOutputPathway interactionsPharmaceutical PreparationsPhenotypePhylogenetic AnalysisPhylogeneticsPhysiologyResearchResearch ResourcesResourcesShapesSumTherapeuticVariantVariationalimentary tractanti-bacterialanti-malarial agentsanti-malarial drugsautoimmune conditionautoimmune disorderautoimmunity diseasebalancebalance functionbile acid metabolismbile metabolismbiologiccommunity microbescomparative genomicscomputer biologydigestive canaldigestive tract microbiomediscover genesdrug/agententeric microbiomefecal microbial transplantationfecal microbiome transplantationfecal microbiota transplantfecal microbiota transplantationfecal transplantfecal transplantationgastrointestinal microbiomegene discoverygut microbiomegut-associated microbiomehost microbe associationhost microbe relationshiphost microbiomehost-microbe interactionshost-microbial interactionshost-microorganism interactionshuman-associated microbiomeintestinal biomeintestinal microbiomeintraoral drug deliverylab assignmentlab experimentlaboratory activitylaboratory assignmentlaboratory exerciselaboratory experimentliving systemmalignancymicrobe communitymicrobialmicrobial communitymicrobiome researchmicrobiome sciencemicrobiome studiesmicroorganism communitymodel of animalmodel organismneoplasm/cancerpathwaypolymicrobial communityprogramsrational designresponsetooltranslational applicationstransplant therapytransplant treatmenttransplantation therapytransplantation treatment
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PROJECT SUMMARY / ABSTRACT
The ecological concept of diversity is deceptively simple: what organisms are present and how are they

distributed. The advent of high-throughput sequencing enabled more than a decade of observational human

microbiome studies; however, these studies frequently established correlation, but not causation, between

microbial…

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Decoding Microbial Diversity in the Human Gut Microbiome — PENNSYLVANIA STATE UNIVERSITY, THE | UNITED STATES | Aug 2023 | Dev Procure