grant
Corneal stromal keratocyte modeling from human cornea organoids
Organization NEW YORK UNIVERSITY SCHOOL OF MEDICINELocation NEW YORK, UNITED STATESPosted 15 Apr 2026Deadline 31 Mar 2030
NIHUS FederalResearch GrantFY20263-D3-Dimensional3DAddressAdherent CultureArchitectureBasal Transcription FactorBasal transcription factor genesBiocompatible MaterialsBiologic ModelsBiological ModelsBiomaterialsBlindnessBody TissuesBone-Derived Transforming Growth FactorCell BodyCell Communication and SignalingCell Culture TechniquesCell DifferentiationCell Differentiation processCell FunctionCell LocomotionCell MigrationCell MovementCell PhysiologyCell ProcessCell SignalingCell SurvivalCell TherapyCell ViabilityCell-Extracellular MatrixCellsCellular FunctionCellular MigrationCellular MotilityCellular PhysiologyCellular ProcessCicatrixCo-cultureCocultivationCocultureCoculture TechniquesCold-Insoluble GlobulinsCollagenCollagen Type IIIColoring AgentsComplexCorneaCornea TransplantationCorneal GraftingCorneal InjuryCorneal StromaCorneal TransplantationDataDebridementDevelopmentDyesECMElectron MicroscopyEndothelial CellsEngineering / ArchitectureEnvironmentEpithelial CellsEpitheliumEquilibriumExtracellular MatrixFN1FibroblastsFibronectin 1FibronectinsFutureGene ExpressionGeneral Transcription Factor GeneGeneral Transcription FactorsGenesHumanImmuneImmune signalingImmunesInfectionInjuryIntracellular Communication and SignalingKeratoconusKeratoplastyKnock-outKnockoutLETS ProteinsLabelLarge External Transformation-Sensitive ProteinLeannessLinkMesenchymal Progenitor CellMesenchymal Stem CellsMesenchymal progenitorMesenchymal stromal/stem cellsMiceMice MammalsMilk Growth FactorModel SystemModelingModern ManMonolayer cultureMurineMusMyofibroblastOpsonic GlycoproteinOpsonic alpha(2)SB GlycoproteinOrganoidsPhenotypePlatelet Transforming Growth FactorProductionProgenitor CellsPropertyRNA SequencesReceptor ProteinResearch ResourcesResolutionResourcesScarsSignal TransductionSignal Transduction SystemsSignalingSomatic CellSourceStandardizationStromal CellsSubcellular ProcessTGF BTGF-Beta Type II ReceptorTGF-betaTGF-beta ReceptorsTGF-Ξ²TGF-Ξ² ReceptorsTGFBR2TGFBR2 geneTGFbetaTGFΞ²TechniquesTestingTherapeuticThinnessTissue DonorsTissue HarvestingTissuesTranscription Factor Proto-OncogeneTranscription factor genesTransforming Growth Factor betaTransforming Growth Factor beta ReceptorsTransforming Growth Factor Ξ² ReceptorsTransforming Growth Factor-Beta Family GeneWound Repairalpha 2-Surface Binding Glycoproteinbalancebalance functionbiological materialbiological signal transductioncell based interventioncell culturecell culturescell mediated interventioncell mediated therapiescell motilitycell-based therapeuticcell-based therapycellular differentiationcellular therapeuticcellular therapycicatrix cornealcornealcorneal epithelial wound healingcorneal fibrosiscorneal keratoplastycorneal scarcorneal transplantcorneal woundcorneal wound healingdevelopmentaldrug developmentfetalhiPSChuman iPShuman iPSChuman induced pluripotent cellhuman induced pluripotent stem cellshuman inducible pluripotent stem cellshuman inducible stem cellsin vivoinduced human pluripotent stem cellsinjuredinjurieslimbalmesenchymal stromal cellmesenchymal stromal progenitor cellsmesenchymal-derived stem cellsmigrationmonolayernovelpilot testprogenitor cell differentiationprogenitor differentiationreceptorregeneration potentialregenerativeregenerative potentialresolutionsresponserestorationscRNA sequencingscRNA-seqsingle cell RNA-seqsingle cell RNAseqsingle cell expression profilingsingle cell transcriptomic profilingsingle-cell RNA sequencingspatial RNA sequencingspatial gene expression analysisspatial gene expression profilingspatial resolved transcriptome sequencingspatial transcriptome analysisspatial transcriptome profilingspatial transcriptome sequencingspatial transcriptomicsspatially resolved transcriptomicsspatio transcriptomicsspheroidsstem and progenitor differentiationstem cell differentiationstem cellsstromal progenitorstromal stem cellthree dimensionaltranscription factortransforming growth factor-beta type II receptortransforming growth factor-Ξ² type II receptorvision lossvisual losswound healingwound recoverywound resolution
Sign up free to applyApply link Β· pipeline Β· email alerts
or
β or βGet email alerts for similar roles
Description preview
Scarring of the stroma, the central layer of the cornea, due to Injury or infection, and severe stromal thinning
due to keratoconus, cause corneal blindness worldwide. Cornea transplantation is often the only cure for many
of these conditions, but limited supply of donor tissue is a major concern. Cell therapy for the stroma, still underβ¦
π
Start 7-day free trial β $29.99/mo βFull details available on the Agency plan
Unlock the complete grant description, eligibility criteria, contract value, evaluation details and apply link β plus alerts, pipeline tracking, and CSV export.
Agency Plan
7-day free trialUnlock procurement & grants
Upgrade to access active tenders from World Bank, UNDP, ADB and more β with email alerts and pipeline tracking.
$29.99 / month
- πEmail alerts for new matching tenders
- ποΈTrack tenders in your pipeline
- π°Filter by contract value
- π₯Export results to CSV
- πSave searches with one click