grant
Core D-Animal Models of Bone and Joint Injury & Disease
Organization WASHINGTON UNIVERSITYLocation SAINT LOUIS, UNITED STATESPosted 15 Apr 2019Deadline 30 Jun 2029
NIHUS FederalResearch GrantFY2025AddressAgingAnimal BehaviorAnimal ModelAnimal Models and Related StudiesAnimal TestingAnti-InflammatoriesAnti-Inflammatory AgentsAnti-inflammatoryArthralgiaArthritisAssayAtrophic ArthritisAwarenessBehaviorBenchmarkingBest Practice AnalysisBioassayBiocompatible MaterialsBiologicalBiological AgentBiological AssayBiological ProductsBiologyBiomaterialsBiomechanicsBlood SerumBody TissuesBone DiseasesBone InjuryCOVID-19 affectedCOVID-19 consequenceCOVID-19 effectCOVID-19 impactCOVID-19 impactedCell BodyCellsCharacteristicsCollaborationsCommunitiesDegenerative ArthritisDegenerative polyarthritisDevelopmentDiabetes MellitusDiseaseDisease ManagementDisorderDisorder ManagementDysfunctionEducation and TrainingEpidemicEuthanasiaEvaluationFractureFracture HealingFresh TissueFunctional disorderFundingGenesGoalsGrantGuidelinesHealthHistologicHistologicallyHistologyImageImmunohistochemistryImmunohistochemistry Cell/TissueImmunohistochemistry Staining MethodInflammationInflammatoryInstructionInvestigatorsJoint DiseasesJoint PainJointsKnowledgeLocomotionMeasuresMechanicsMedicineMercy KillingMetabolic DiseasesMetabolic DisorderMiceMice MammalsModelingMolecularMouse StrainsMurineMusMusculoskeletalObesityOsteoarthritisOsteoarthrosisPainPainfulPathologyPhysiopathologyProcessProteinsProtocolProtocols documentationQuality ControlReagentReproducibilityResearchResearch PersonnelResearch ResourcesResearchersResourcesRestRheumatoid ArthritisRodent ModelRunningSamplingSerumSourceSupervisionSwellingSymptomsTestingTherapeutic InterventionThesaurismosisTimeTissue BanksTissue CollectionTissue repositoryTissuesTrainingTraining and EducationTraumatic ArthritisTraumatic Arthropathyadiposityarthriticarthropathicarthropathiesarthropathybenchmarkbiobankbiologicbiological materialbiologicsbiomechanicalbiopharmaceuticalbiorepositorybiotherapeutic agentbonebone disorderbone fracturebone fracture healingbone fracture repaircohortcoronavirus disease 2019 consequencecoronavirus disease 2019 effectcoronavirus disease 2019 impactcoronavirus disease-19 impactcorpulencedata integrationdegenerative joint diseasedepositorydevelopmentaldiabetesdisease modeldisorder modelfracture repairfunctional outcomeshypertrophic arthritisimaginginterestintervention therapyjoint damagejoint disorderjoint functionjoint injuryjoint traumamechanicmechanicalmetabolism disordermodel of animalmouse modelmurine modelnew therapeutic approachnew therapeutic interventionnew therapeutic strategiesnew therapy approachesnew treatment approachnew treatment strategynext generationnovel therapeutic approachnovel therapeutic interventionnovel therapeutic strategiesnovel therapy approachoutreachpain reliefpain sensitivitypathophysiologypost-traumatic osteoarthritisprogramsrelieve painrepositoryrheumatic arthritistissue resourcetreadmill
Description preview
ABSTRACT
Rheumatoid arthritis (RA) and osteoarthritis (OA) are highly prevalent conditions that have reached epidemic
proportions in the US and worldwide. These joint diseases are characterized by inflammation, swelling, pain,
and limited mobility. Despite significant advances in developing anti-inflammatory therapies, biologics, and
symptomatic…
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