grant
Core C: Electrophysiology Core
Organization BETH ISRAEL DEACONESS MEDICAL CENTERLocation BOSTON, UNITED STATESPosted 1 Jul 2020Deadline 31 Aug 2030
NIHUS FederalResearch GrantFY2025BrainBrain Nervous SystemCalciumCell BodyCellsCharacteristicsCore FacilityDataElectrophysiologyElectrophysiology (science)EncephalonEnsureGraphHistologyImageImage data archiveImaging ProceduresImaging TechnicsImaging TechniquesImmunohistochemistryImmunohistochemistry Cell/TissueImmunohistochemistry Staining MethodIn VitroInstitutionInvestigatorsLabelMapsMeasuresMonitorNerveNerve CellsNerve Transmitter SubstancesNerve UnitNeural CellNeurocyteNeuronsNeurophysiology / ElectrophysiologyNeurotransmittersPopulationPropertyProtocolProtocols documentationPublicationsPublishingResearch PersonnelResearch ResourcesResearchersResource SharingResourcesScientific PublicationServicesSleepSleep ApneaSleep Apnea SyndromesSleep HypopneaSleep-Disordered BreathingSliceStatistical Data AnalysesStatistical Data AnalysisStatistical Data InterpretationSynapsesSynapticTechniquesUpdateWhole-Cell Recordingsantagonismantagonistcalcium indicatorelectrophysiologicalexperimentexperimental researchexperimental studyexperimentshistological sampleshistological specimenshistology sampleshistology specimensimage archival systemimage archiveimage libraryimage repositoryimagingimaging repositoryimaging studyneurochemicalneurochemistryneuronalnoveloptogeneticspatch clamppicture archivepost-synaptic nervespost-synaptic neuronspostsynapticpostsynaptic nervespostsynaptic neuronsresponsesleep-related breathing disorderstatistical analysissynapsetool
Description preview
Project Summary/Abstract
The Electrophysiology Core (Core C) will provide services for in vitro electrophysiological studies using novel
tools such as optogenetics and in vitro GCaMP6 calcium imaging. We will prepare brain slices, conduct patch-
clamp recordings, channelrhodopsin2 (ChR2)-assisted circuit mapping (CRACM), and Ca2+ imaging studies…
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