grant

Core B Ocular Imaging Core

Organization CLEVELAND CLINIC LERNER COM-CWRULocation CLEVELAND, UNITED STATESPosted 1 Sept 2016Deadline 30 Jun 2026
NIHUS FederalResearch GrantFY2025Animal ModelAnimal Models and Related StudiesAnimalsBody TissuesBrachydanio rerioCenter Core GrantsClinicCollaborationsCommon Rat StrainsComputer softwareConfocal MicroscopyCryosectioningCryoultramicrotomyDanio rerioDarknessDataDedicationsDisease ProgressionDomestic RabbitDoppler OCTEquipmentEyeEyeballFaculty RecruitmentFixationFluorescenceFluorescence Light MicroscopyFluorescence MicroscopyFosteringFreezingFundingFundus photographyGenerationsGrantImageImage AnalysesImage AnalysisImaging ProceduresImaging TechnicsImaging TechniquesImmunohistochemistryImmunohistochemistry Cell/TissueImmunohistochemistry Staining MethodInvestigatorsLaser ElectromagneticLaser RadiationLasersMiceMice MammalsMurineMusNational Institutes of HealthOCT TomographyOphthalmoscopyOptical Coherence TomographyOryctolagus cuniculusP30 AwardP30 GrantP30 MechanismP30 ProgramParaffinParaffin EmbeddingParaffin waxes and Hydrocarbon waxesPathway interactionsPlastic EmbeddingProcessProductivityProtocolProtocols documentationRabbitsRabbits MammalsRatRats MammalsRattusResearchResearch PersonnelResearch ResourcesResearch SupportResearchersResourcesScanningScientistServicesSightSoftwareStaining methodStainsStandardizationSupervisionTalentsTechniquesTechnologyTestingTissue EmbeddingTissue FixationTissue imagingTissuesTrainingTranslational ResearchTranslational ScienceTransmission Electron MicroscopyUnited States National Institutes of HealthVisionVision researchVisual SystemZebra DanioZebra FishZebrafishanimal imagingcell imagingcellular imagingclinical imagingex vivo imagingexperienceeye fundus photographyeye imagingfundus camerahuman imagingimage evaluationimage interpretationimage processingimage-based methodimagingimaging in vivoimaging methodimaging modalityin vivoin vivo imaginginnovateinnovationinnovativeinstrumentinstrumentationmachine learned algorithmmachine learning algorithmmachine learning based algorithmmicroscope imagingmicroscopic imagingmicroscopy imagingmodel of animalocular imagingophthalmic imagingoptical Doppler tomographyoptical coherence Doppler tomographypathwayprogramsrecruitrecruit teachersresearch facultysample fixationteacher recruitmenttissue processingtranslation researchtranslational investigationvision sciencevisual functionvisual science
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Full Description

Abstract
Ocular Imaging Core

The Ocular Imaging Core will provide a variety of imaging modalities to the investigators involved in this P30 Cole Eye

Vision Research Core. The module includes live animal (in vivo) imaging with slit lamp and fundus photography,

scanning laser ophthalmoscopy (SLO) and optical coherence tomography (OCT). It also supports tissue and cellular

imaging (ex vivo) support, providing training and assistance with routine and specialized tissue fixation techniques,

paraffin and plastic tissue embedding, sectioning (paraffin and Cryo) and staining for immunohistochemistry.

Microscope imaging techniques include bright field, dark field, differential interference contrast (DIC), fluorescence,

and confocal microscopy . It also provides help and advice with the morphometric analysis of generated images. Access

to this core module will support NEI R01 funded investigators, help newly recruited investigators obtain data for NEI

R01 grant submissions, foster collaborative interactions between RO1-funded investigators and newly recruited

investigators, attract investigators from other departments to research on the visual system and be a valuable

departmental resource in attracting additional vision scientists to our program as we expand our research faculty.

Grant Number: 5P30EY025585-10
NIH Institute/Center: NIH

Principal Investigator: VERA BONILHA

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