grant

Consortium of Food Allergy Research Clinical Research Center at Cincinnati Children's Hospital Medical Center (CoFAR-CRC:CCHMC)

Organization CINCINNATI CHILDRENS HOSP MED CTRLocation CINCINNATI, UNITED STATESPosted 1 Mar 2024Deadline 28 Feb 2031
NIHUS FederalResearch GrantFY20260-11 years old2,3,7,8-Tetrachlorodibenzo-p-dioxin Receptors21+ years old8 year old8 years of ageAH ReceptorsAddressAdherenceAdultAdult HumanAirAllergen ImmunotherapyAllergensAllergic DiseaseAllergic to foodAllergyAllergy immunotherapyAllergy to foodAntiproteasesAryl Hydrocarbon ReceptorB cell receptorB-Cell Antigen ReceptorBacteriaBasic ResearchBasic ScienceBasophilic GranulocyteBasophilsBiopsyBloodBlood BasophilBlood Reticuloendothelial SystemCaringCell Communication and SignalingCell DifferentiationCell Differentiation processCell SignalingChildChild YouthChildren (0-21)Children's HospitalClassificationClinicClinical ResearchClinical StudyClinical TrialsCollectionCommunitiesDataData BasesDatabasesDevelopmentDioxin ReceptorsDiseaseDisorderDoctor of PhilosophyDoseEXTMREducationEducational aspectsEndopeptidase InhibitorsEnterocolitisEnvironmentEnvironmental ExposureEnvironmental FactorEnvironmental Risk FactorEosinophilic EsophagitisEpitheliumEsophagusExtramuralExtramural ActivitiesFacultyFaculty EducationFaculty TrainingFamilyFoodFood AllergyFood HypersensitivityFundingGene TranscriptionGenesGenetic TranscriptionGuidelinesHolidaysHorny LayerIgEImmunoglobulin EImmunologyIndividualInfantIntracellular Communication and SignalingJournalsKnowledgeLeadershipLigandsLong-term cohort studyLongitudinal cohort studyMagazineMaintenanceMediatingMedical centerMentorsMetabolicMinorityMolecularMolecular FingerprintingMolecular ProfilingMulti-Institutional Clinical TrialMulti-center clinical trialMulti-site clinical trialMulticenter clinical trialMultisite clinical trialNational Institutes of HealthNuclear TranslocatorOralPathogenesisPathologyPathway interactionsPatient CarePatient Care DeliveryPatient SchedulesPatientsPatternPediatric HospitalsPeptidase InhibitorsPeptide Hydrolase InhibitorsPeptide Peptidohydrolase InhibitorsPh.D.PhDPharmaceutical AgentPharmaceuticalsPharmacologic SubstancePharmacological SubstancePhasePolyaromatic Hydrocarbon ReceptorsPopulationPreparednessPrevalenceProceduresProductivityProtease AntagonistsProtease InhibitorProteinase InhibitorsProteinsProtocolProtocols documentationPublishingR-Series Research ProjectsR01 MechanismR01 ProgramRNA ExpressionReadinessRegistriesResearchResearch GrantsResearch Project GrantsResearch ProjectsRoleSamplingServicesSignal TransductionSignal Transduction SystemsSignalingSolidStratum corneumStructureSystematicsTCDD ReceptorsTeacher EducationTeacher EducatorTeacher PreparationTeacher Professional DevelopmentTeacher TrainingTherapeuticTranscriptionTranslational ResearchTranslational ScienceUnited States National Institutes of HealthWorkadulthoodage 8age 8 yearsarmaryl hydrocarbonsbiobankbiological signal transductionbiorepositorycare for patientscare of patientscaring for patientscellular differentiationclinical careclinical centerdata basedevelopmentaldietaryeight year oldeight years of ageenvironmental riskexperienceexposure to environmental agentsexposure to environmental factorsexposure to environmental stimuliexposure to environmental substancesfaculty developmentfaculty professional developmentfood allergenimprovedinstructor trainingkidsmicrobiomemolecular profilemolecular signaturemultidisciplinarynew markernovel biomarkernovel markeroral immunotherapypathwaypatient populationpharmaceuticalpharmacologicpreservationprimary outcomeprogramsprospectiveprotective effectrecruitscRNA sequencingscRNA-seqsensorsingle cell RNA-seqsingle cell RNAseqsingle cell expression profilingsingle cell transcriptomic profilingsingle-cell RNA sequencingsocial roleteacher developmenttoxicanttranslation researchtranslational investigationyoungster
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PROJECT SUMMARY
The proposed Consortium of Food Allergy Research Clinical Research Center: Cincinnati Children's Hospital

Medical Center (CoFAR-CRC:CCHMC) aims to bring the experience, expertise, and scientific productivity and

the diverse patient populations of CCHMC to CoFAR. The patient population seen in the clinics and

participating in the…

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