grant
Confirmatory Efficacy Trial of a Traditional vs. Gamified Attention Bias Modification for Depression
Organization UNIVERSITY OF TEXAS AT AUSTINLocation AUSTIN, UNITED STATESPosted 20 Jul 2023Deadline 31 May 2028
NIHUS FederalResearch GrantFY202521+ years oldActive Follow-upAdultAdult HumanAfter CareAfter-TreatmentAftercareAreaAttentionBasic ResearchBasic ScienceCell Communication and SignalingCell SignalingClinical TrialsCognitiveDataData AnalyticsDepressed moodDevelopmentEffectivenessEmotional DepressionExperimental TherapiesFundingGoalsInterventionInterviewerIntracellular Communication and SignalingInvestigational TherapiesInvestigational TreatmentsLiteratureMaintenanceMajor Depressive DisorderMeasuresMediatingMediationMediatorMental DepressionMental HealthMental HygieneMethodsModificationNIMHNational Institute of Mental HealthNegotiatingNegotiationOutcomePatient Self-ReportPersonsPopulationProtocolProtocols documentationPsychological HealthPsychopathologyPublic HealthPublishingQOL improvementRecoveryReportingResearchRoleSamplingSelf-ReportSeveritiesSignal TransductionSignal Transduction SystemsSignalingStimulusSymptomsTestingTrainingTreatment ProtocolsTreatment RegimenTreatment ScheduleWorkabnormal psychologyactive followupadulthoodalleviate symptomameliorating symptomanxiousattentional biasbehavior measurementbehavioral measurebehavioral measurementbiological signal transductionclinical depressioncognitive trainingconfirmatory efficacy trialconfirmatory trialdecrease symptomdepresseddepressiondepression symptomdepressivedepressive symptomsdetermine efficacydevelop therapydevelopmentalefficacious therapyefficacious treatmentefficacy analysisefficacy assessmentefficacy determinationefficacy evaluationefficacy examinationefficacy testingefficacy trialevaluate efficacyexamine efficacyexperienceexperimental therapeutic agentsexperimental therapeuticseye trackingfewer symptomsfollow upfollow-upfollowed upfollowupgazeimprovedimprovements in QOLimprovements in quality of lifeinsightintervention developmentmajor depressionmajor depression disordermobile appmobile applicationmobile device applicationnegative affectnegative affectivitypost treatmentpreventpreventingpsychosocialquality of life improvementrandomized, clinical trialsreduce symptomsrelieves symptomsresponsesadnesssocial rolesustained attentionsymptom alleviationsymptom reductionsymptom reliefsymptom treatmentsymptomatic treatmenttherapy developmenttreat symptomtreatment developmenttrial comparingvisual tracking
Description preview
Project Summary/Abstract
The overall goal of this project is to conduct a well-powered confirmatory efficacy trial comparing a gamified,
attention bias modification (ABM) mobile application and traditional ABM to sham ABM among adults with
elevated symptoms of depression. The proposed R01 efficacy trial follows the NIMH intervention development…
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