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Close the GAP: Glycemic control after Antenatal corticosteroids in women with Pregestational diabetes

Organization UNIVERSITY OF ALABAMA AT BIRMINGHAMLocation BIRMINGHAM, UNITED STATESPosted 1 Dec 2020Deadline 30 Nov 2025 ⚠️
NIHUS FederalResearch GrantFY2025Adrenal Cortex HormonesAdult-Onset Diabetes MellitusAlabamaAlgorithmsAwardBehavioral SciencesBiometricsBiometryBiostatisticsCaringClient satisfactionClinicalClinical ManagementClinical TrialsContinuous Glucose MonitorCorticoidsCorticosteroidsD-GlucoseDataDevelopment PlansDextroseDiabetes MellitusDiscipline of obstetricsEndocrinologyEnrollmentEnsureExclusionFundingGestationGlucoseGoalsGrantHealth ResourcesHigh Risk WomanHomeHumulin RHyperglycemiaHyperinsulinemiaHyperinsulinismInfusionInfusion proceduresInsulinInterdisciplinary ResearchInterdisciplinary StudyInterventionInvestigatorsKetosis-Resistant Diabetes MellitusKnowledgeMaternal and Child HealthMaturity-Onset Diabetes MellitusMeasuresMentorsMetabolic dysfunctionMetabolism and EndocrinologyMulti-Institutional Clinical TrialMulti-center clinical trialMulti-center trialMulti-site clinical trialMulticenter TrialsMulticenter clinical trialMultidisciplinary CollaborationMultidisciplinary ResearchMultisite clinical trialNIDDMNeonatalNeonatal respiratory morbidityNeonatologyNon-Insulin Dependent DiabetesNon-Insulin-Dependent Diabetes MellitusNoninsulin Dependent DiabetesNoninsulin Dependent Diabetes MellitusNovolin RObstetricsOutcomePatient SatisfactionPopulationPositionPositioning AttributePregnancyPregnancy ComplicationsPregnant WomenPremature BirthPrematurely deliveringPreterm BirthRandomizedRandomized, Controlled TrialsRecommendationRegimenRegular InsulinResearchResearch DesignResearch PersonnelResearchersRetrospective StudiesSample SizeScientistSecureSlideSlow-Onset Diabetes MellitusSpecific qualifier valueSpecifiedStable Diabetes MellitusStandardizationStructureStudy TypeT2 DMT2DT2DMTestingTimeTitrationsTrainingTraining ProgramsType 2 Diabetes MellitusType 2 diabetesType II Diabetes MellitusType II diabetesUnited StatesUniversitiesVariantVariationWomanWritingadult onset diabetesantenatalantepartumat-risk femalesat-risk womencareer developmentclinical practicecompare to controlcomparison controlcomplications during pregnancycontinuous blood glucose monitorcontinuous blood sugar monitorcontinuous glucose measurementcontinuous sugar monitorcostdata acquisitiondata acquisitionsdiabetesefficacy testingenrollevidence baseexpectant motherexpectant womenexpecting motherexpecting womenexperiencefemale outcomesfemales at high riskfetalglucometerglucose meterglucose monitorglycemic controlhigh risk femaleshigh risk grouphigh risk individualhigh risk peoplehigh risk populationhomeshyperglycemicimplementation scienceimprovedindividuals who are pregnantinfusionsketosis resistant diabetesmaternal hyperglycemiamaternal riskmaturity onset diabetesmultidisciplinaryneonatal morbidityneonatal outcomeneonatenewborn morbiditynon-diabeticnondiabeticoutcomes among femalesoutcomes among womenoutcomes in femalesoutcomes in womenpeople who are pregnantpregnancy-related complicationspregnant femalespregnant motherspregnant peoplepregnant populationspremature childbirthpremature deliverypreterm deliveryprospectivepulmonaryrandomisationrandomizationrandomized control trialrandomized, clinical trialsrandomly assignedrespiratoryside effectskill acquisitionskill developmentskillsstudy designtheoriesthose who are pregnanttreatment strategytype 2 DMtype II DMtype two diabeteswomen at high riskwomen who are pregnantwomen's outcomes

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ABSTRACT
There is a fundamental gap in understanding the maternal and neonatal effects of antenatal corticosteroid

(ACS) administration in women with threatened preterm birth (PTB) who have type 2 diabetes mellitus (T2DM).

Since the initial discovery of ACS for neonatal benefit in 1972, more than 40 randomized controlled trials have

been performed…

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