grant

Clinical Research Core

Organization UNIVERSITY OF FLORIDALocation GAINESVILLE, UNITED STATESPosted 1 Jun 2007Deadline 31 Mar 2027
NIHUS FederalResearch GrantFY2026AddressAdherenceAffectAgingAmericanAncillary StudyAreaBehavioralBehavioral ResearchBiologicalBudgetsClinicalClinical ResearchClinical StudyClinical TrialsCognitiveCollaborationsCollectionDataDecline in mobilityDecrease in mobilityDecreased mobilityDevelopmentDiminished mobilityDisability preventionDisciplineEducationEducational aspectsElderlyEnvironmentEnvironmental FactorEnvironmental Risk FactorEthnic OriginEthnicityFloridaFosteringFundingFutureGoalsHuman ResourcesInfrastructureInterdisciplinary ResearchInterdisciplinary StudyInterventionIntervention StudiesInvestigationInvestigatorsJointsLeadLeadershipManpowerMeasuresMentorsMinorityMobility declineMobility impairmentMultidisciplinary CollaborationMultidisciplinary ResearchNational Institutes of HealthNutrition ResearchNutritional StudyObservational StudyOlder PopulationPainPainfulPathway interactionsPatient RecruitmentsPb elementPharmacological StudyPharmacology StudyPhase 2 Clinical TrialsPhase II Clinical TrialsPhysical FunctionPhysiologicPhysiologicalPilot ProjectsPreventing disabilitiesProgress ReportsRaceRacesRecordsReduced mobilityReduction in mobilityResearchResearch PersonnelResearch ResourcesResearch SpecimenResearchersResourcesRoleScienceScientistSpecimenTechnologyTrainingTranslational ResearchTranslational ScienceTranslationsUnited States National Institutes of HealthUniversitiesUniversity resourcesWalkingadvanced agebehavior studybehavioral studybiologiccareer developmentclinical investigationclinical translationclinical trial implementationclinically translatabledecline in functiondecline in functional statusdesigndesigningdevelopmentaldisparity in healthearly clinical trialearly phase clinical trialeducation researchefficacy studyenvironmental riskfaculty researchfull professorfunctional declinefunctional disabilityfunctional status declinegeriatrichealth disparityheavy metal Pbheavy metal leadhigh riskimplementation of clinical trialsimprovedimproved mobilityinnovateinnovationinnovativeintervention designintervention researchinterventional researchinterventional studyinterventions researchmobility enhancementmobility improvementneuralneural controlneural regulationneuromodulationneuromodulatoryneuroregulationobservational research studyobservational surveyolder adultolder adulthoodolder groupsolder individualsolder personoptimized mobilityparticipant recruitmentpathwaypersonnelphase II protocolpilot studypre-clinical researchpre-clinical studypreclinical researchpreclinical studyprotocol developmentracialracial backgroundracial originrecruitresearch facilityresearch facultyresearch studyresponsesenior citizensenior facultysexsocialsocial rolestandardize measuresuccesssynergismtherapy designtranslationtranslation researchtranslational investigationtreatment design
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Full Description

The Clinical Research Core (RC1) is a key resource for the University of Florida (UF) Older Americans Independence Center (OAIC), providing the resources and expertise for conducting research across the spectrum of clinical investigation, including clinical trials, as well as observational studies of biological and behavioral factors related to promotion of mobility and independence. The Core’s primary goal is to encourage and facilitate clinical translational research focused on promotion of mobility and independence. The RC1 has three Specific Aims: 1. Aim 1: Provide the resources and intellectual environment to facilitate clinical research, team science, and education of OAIC REC Scholars related to promotion of mobility and independence. 2.

Aim 2: Promote and facilitate translation of pre-clinical and pilot studies into clinical trials in older persons. 3. Aim 3: Improve our understanding of behavioral, biological, cognitive, and social/environmental factors that may affect responses to interventions, designed to promote mobility and independence in older adults. The RC1 provides resources and personnel (including U01 and R01 NIH funded investigators) to support the development and implementation of clinical trials, including pharmacologic, nutritional and behavioral interventions, and observational studies addressing factors contributing to mobility impairment in older adults and implications for functional decline and disability. Building on close collaborations with other OAIC cores, the RC1 will support pilot/exploratory projects, developmental projects, and external projects.

The Core will also provide senior level Investigators with established track records as mentors for research education to lead each of these goals, providing expertise and promoting a rich environment for early-stage faculty research and senior faculty collaboration.

Grant Number: 5P30AG028740-20
NIH Institute/Center: NIH

Principal Investigator: Stephen Anton

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