grant

Clinical Decision Supports to Prevent Teen Substance Use in Pediatric Primary Care

Organization YALE UNIVERSITYLocation NEW HAVEN, UNITED STATESPosted 15 May 2025Deadline 30 Apr 2027
NIHUS FederalResearch GrantFY20260-11 years old12 year old12 years of age9 year old9 years of ageAdolescentAdolescent YouthAdoptionAgeAlcohol Chemical ClassAlcoholsCare GiversCaregiversCaringChildChild RearingChild YouthChildhoodChildren (0-21)CitiesClinicalClinical InformaticsCommunitiesCommunity prevention programsComplexConnecticutConsolidated Framework for Implementation ResearchConsolidated Framework for Implementation ScienceConsolidated Framework for Implementing ChangeCounselingDedicationsDisciplineEconomic IncomeEconomical IncomeEffectivenessEmotionalEnrollmentEnvironmental FactorEnvironmental Risk FactorFamilyFederally Qualified Health CenterFutureHealthHealth CareHealth PromotionHealth Services EvaluationHealth Services ResearchHospital AdmissionHospitalizationHouseholdIncomeIndividualInfrastructureLinkLow incomeMaintenanceMedical Care ResearchNeighborhoodsNon-Profit OrganizationsNonprofit OrganizationsOutcomeParentingParenting behaviorParentsPatientsPersonsPhasePositionPositioning AttributePreventative interventionPreventionPrevention ResearchPrevention programPrimary CareProcessPublic HealthQualitative MethodsRE-AIMRandomizedRandomized, Controlled TrialsReach, Effectiveness, Adoption, Implementation, and MaintenanceRecommendationResearchResearch ResourcesResourcesRiskSalutogenesisScienceScientistServicesTHC co-useTHC useTeenTeenagersTestingTetrahydrocannabinol co-useTetrahydrocannabinol useTimeTransportationVaccinationVariantVariationWell Child VisitsWell child checksWell child checkupsWell child examadolescent substance useage 12age 12 yearsage 9age 9 yearsagescannabis usechild routine wellness visitschild wellness visitchildrearingclinical decision supportclinician factorsclinician-level factorsdesigndesigningelderly patientenrollenvironmental riskevidence baseexperiencefederal poverty levelhealth and care deliveryhealth care deliveryhealth delivery systemshealth services deliveryhealth services infrastructurehealth system infrastructurehealthcare delivery infrastructurehealthcare infrastructurehealthcare system infrastructureimplementation researchimplementation strategyimprovedincomesintervention for preventionjuvenilejuvenile humankidslower income familiesmarijuana usemultidisciplinarynine year oldnine years of agenovelolder patientopiate deathsopiate mortalityopioid deathsopioid mortalityopioid overdose deathopioid related deathparentparent monitoringparental monitoringpediatricpediatric preventive visitpediatric well visitphysician factorsphysician-level factorspre-adolescentpreadolescencepreteenpreventprevent substance usepreventingprevention interventionprevention servicepreventional intervention strategypreventive interventionprimary care patientprogramspromoting healthprovider factorsprovider-level factorsqualitative reasoningrandomisationrandomizationrandomized control trialrandomly assignedreach, efficacy, adoption, implementation, and maintenancereduced substance usereduction in substance useroutine child health visitscreeningscreeningsservices researchskillssocial determinantssocial factorssocio-economicsocio-economicallysociodeterminantsocioeconomicallysocioeconomicsstandard carestandard treatmentstrategies for implementationsubstance usesubstance use among adolescentssubstance use among youthsubstance use preventionsubstance use reductionsubstance usingsupport toolsteen yearsteenagetooltwelve year oldtwelve years of ageuptakeusabilityuser centered designyoungsteryouth substance use
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Full Description

PROJECT SUMMARY
Improving the reach and adoption of evidence-based prevention programming is a top priority for substance use prevention science. In the U.S., complex interactions between social and environmental factors and broader structural conditions contribute to differences in substance use-related health outcomes. Prior research has produced numerous evidence-based substance use prevention interventions, including several that are family-focused. Family-focused programs promote protective parenting skills—such as warmth, parental monitoring, and positive discipline—to reduce substance use risk in adolescents. Although effective, family-focused programs have limited reach among communities served by federally qualified health centers. Integrating family-focused programs into existing healthcare infrastructures can help overcome these challenges. Federally qualified health centers (FQHCs) deliver primary care to over 30 million patients nationwide and are well-positioned to expand the adoption and reach of family-focused prevention programs. We propose one of the first studies to co-design (R61) and test (R33) a novel implementation strategy to Support Pre-Adolescents and families’ linkage to substance use pRevention services in primary Care (SPARC). Partnering with caregivers, clinicians, FQHC leaders, and a statewide nonprofit organization that supports FQHC capacity in Connecticut, this study will take place at a large FQHC serving more than 18,000 children in New Haven, CT. The study brings together an interdisciplinary team with expertise in adolescent substance use prevention, implementation research, health services research, and clinical informatics. SPARC will include a co-designed clinical recommendation, clinical decision support tool, and referral process to link caregivers of 9–12-year-old primary care patients to a locally delivered family-focused substance use prevention program, Guiding Good Choices. Guiding Good Choices has demonstrated effectiveness in preventing adolescent substance use by strengthening protective parenting skills. Guided by the Consolidated Framework for Implementation Research and RE-AIM frameworks, during the R61 Planning Phase, we will iteratively develop the SPARC implementation strategy with input from multiple stakeholder groups (R61 Aim 1) and evaluate its usability, acceptability, and feasibility in routine clinical settings (R61 Aim 2). Upon successful completion of R61 milestones, we will examine SPARC’s impact on Guiding Good Choices adoption and reach through a pragmatic randomized controlled trial of clinicians (R33 Aim 1). We will also examine organizational, clinician-level (R33 Aim 2), and caregiver-level (R33 Aim 3) factors associated with variation in adoption and reach. Completion of the proposed studies will inform future efforts to expand the delivery of evidence-based substance use prevention programs across FQHC settings.

Grant Number: 5R61DA062103-02
NIH Institute/Center: NIH

Principal Investigator: Deepa Camenga

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