grant

Circuit functions of fast-spiking interneurons in the main olfactory bulb

Organization LEHIGH UNIVERSITYLocation BETHLEHEM, UNITED STATESPosted 1 Jul 2023Deadline 30 Jun 2028
NIHUS FederalResearch GrantFY20254-Aminobutanoic Acid4-Aminobutyric Acid4-amino-butanoic acidAD dementiaAcuteAddressAlzheimer Type DementiaAlzheimer disease dementiaAlzheimer sclerosisAlzheimer syndromeAlzheimer'sAlzheimer's DiseaseAlzheimers DementiaAminalonAminaloneAmmon HornArchitectureBehaviorBiologic ModelsBiological ModelsBrainBrain Nervous SystemBrain regionCCKCell BodyCell Communication and SignalingCell SignalingCellsCholecystokininCodeCoding SystemComplexConnector NeuronConsensusCornu AmmonisDataDendritesDependenceDistalElementsEncephalonEngineering / ArchitectureGABAGenerationsGeneticGlutamate ReceptorHippocampusHistologyHumanImageIndividualIntercalary NeuronIntercalated NeuronsInterneuron functionInterneuronsInternuncial CellInternuncial NeuronIntracellular Communication and SignalingInvestigationIon ChannelIonic ChannelsKnowledgeLateralLinkMammaliaMammalsMeasuresMediatingMembrane ChannelsMiceMice MammalsModel SystemModern ManMorphologyMurineMusNeocortexNerve CellsNerve UnitNervous System DiseasesNervous System DisorderNeural CellNeurocyteNeurologic DisordersNeurological DisordersNeuronsOlfactionOlfactory PathwaysOlfactory systemOrganization ChartsOutputPancreozyminParalysis AgitansParkinsonParkinson DiseasePatternPerceptionPeripheralPharmacologyPrevalencePrimary ParkinsonismPrimary Senile Degenerative DementiaProcessPropertyRecurrenceRecurrentRegulationRodentRodentiaRodents MammalsRoleSensorySensory DeprivationSignal TransductionSignal Transduction SystemsSignalingSiteSliceSmellSmell PerceptionStimulusStudy modelsSynapsesSynapticTarget PopulationsTestingUropancreozyminViralWhole-Cell RecordingsWorkbiological signal transductioncell typeexcitatory neurongamma-Aminobutyric Acidgranule cellhippocampalhomotypical corteximaginginhibitory neuroninnervationinsightisocortexneopalliumnerve supplyneuralneurological diseaseneuronalodor perceptionolfactory bulbolfactory circuitryolfactory circuitsolfactory perceptionorganizational structurepostsynapticprimary degenerative dementiareconstructionsenile dementia of the Alzheimer typesensory inputsimulationsocial rolesynapsesynapse inhibitionsynaptic inhibitionγ-Aminobutyric Acid
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PROJECT SUMMARY/ABSTRACT
The olfactory system is critical to several aspects of behavior and survival in mammals, including humans. The

olfactory bulb is the first processing station of the olfactory system and constitutes an exceptional model system

for the study of neural coding, capable of encoding a highly complex sensory space within a…

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Circuit functions of fast-spiking interneurons in the main olfactory bulb — LEHIGH UNIVERSITY | UNITED STATES | Jul 2023 | Dev Procure