grant

Chemical Strategies to Map Bacterial Response to Environmental Change

Organization UNIVERSITY OF MINNESOTALocation MINNEAPOLIS, UNITED STATESPosted 1 Jun 2024Deadline 31 May 2029
NIHUS FederalResearch GrantFY2025ATP-protein phosphotransferaseAdjuvantAnabolismAntibiotic AgentsAntibiotic DrugsAntibiotic ResistanceAntibioticsAreaBacteriaBacterial Antibiotic ResistanceBacterial InfectionsBiochemistryBiological ChemistryBiologyCell BodyCell Communication and SignalingCell SignalingCell SurvivalCell ViabilityCell WallCell divisionCellsCellular ExpansionCellular GrowthChemicalsCytoplasmDevelopmentDiseaseDisorderDisparateEnvironmentEnzyme GeneEnzymesExposure toFamilyFoundationsFutureGenomeGrantInternetIntracellular Communication and SignalingInvestigationKinase Family GeneKnowledgeLabelLeadLeadershipLibrariesLigandsMapsMass Photometry/Spectrum AnalysisMass SpectrometryMass SpectroscopyMass SpectrumMass Spectrum AnalysesMass Spectrum AnalysisMethodsMicrobiologyMiscellaneous AntibioticNational Institutes of HealthOrganismPb elementPenicillin-Binding ProteinsPeriplasmic SpacePlanetsProtein FamilyProtein KinaseProteinsQualifyingResearchResistance to antibioticsResistance to infectionResistant to antibioticsRoleSightSignal TransductionSignal Transduction SystemsSignalingStimulusTestingTransmissionUnited States National Institutes of HealthVirulenceVisionWWWWorkantibiotic drug resistanceantibiotic resistantantibiotic resistant bacteriabacteria infectionbacterial antibiotic resistantbacterial diseasebacterial resistance to antibioticbeta lactam antibioticbeta-Lactamsbiological signal transductionbiosynthesiscell growthchemical synthesiscombatdevelopmentaldifferentiation factorsenvironmental changeenvironmental stressesenvironmental stressorglycogen synthase a kinaseheavy metal Pbheavy metal leadhistidine kinasehydroxyalkyl protein kinaseinfection resistanceliving systemmorphogenic factorsmorphogensnovelperiplasmphosphorylase b kinase kinaseprotein-histidine kinaseresponsesocial roletooltransmission processvisual functionwebworld wide webβ lactam antibioticβ-Lactams
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Description preview

The Carlson Group applies the diverse tools of chemical biology to understand how bacteria harness their
limited genome to inhabit nearly every ecological niche on our planet. These “simple” single-celled organisms

are remarkable in their ability to respond to and survive in the presence of diverse environmental stressors. This

is largely…

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