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Cell-cell signaling in archaea: How Haloferax volcanii talk to each other

Organization UNIVERSITY OF PENNSYLVANIALocation PHILADELPHIA, UNITED STATESPosted 1 Apr 2024Deadline 18 Dec 2025 ⚠️
NIHUS FederalResearch GrantFY2025AgarAnabolismAnalytic ChemistryAnalytical ChemistryAnti-Bacterial AgentsArchaeaArchaebacteriaArchaeobacteriaArchaeonAreaAssayBioassayBiological AssayBypassCell BodyCell Communication and SignalingCell ShapeCell SignalingCell secretionCell to Cell Communication and SignalingCell-Cell SignalingCellsCellular SecretionCellular biologyChemical FractionationChemistryChromatographyCo-ImmunoprecipitationsCoinCollaborationsCommunicationComplementComplement ProteinsComplexCustomDNA NucleasesDNA mutationDNaseDataDeoxyribonucleasesDevelopmentDiseaseDisease OutcomeDisorderEsteroproteasesFRACNFlagellaFluorescence Activated Cell Sorting FractionationFluorescence-Activated Cell SortingFluorescence-Activated Cell SortingsFractionationFractionation RadiotherapyFunctional MetagenomicsGene ExpressionGeneHomologGeneralized GrowthGenesGenetic ChangeGenetic defectGenetic mutationGenomic SegmentGrowthHaloferax volcaniiHealthHomologHomologous GeneHomologous ProteinHomologueHumanHuman MicrobiomeIndustryIntracellular Communication and SignalingInvestigationLeadLibrariesLifeLinkMass Photometry/Spectrum AnalysisMass SpectrometryMass SpectroscopyMass SpectrumMass Spectrum AnalysesMass Spectrum AnalysisMediatingMedicineMetagenomicsMicrobeMicrobial BiofilmsMicrobiomicsModelingModern ManMolecularMorphologyMotilityMutationNutrientNutrient DepletionOrganic SolventsOrganic solvent productPathway interactionsPatternPb elementPeptidasesPeptide HydrolasesPhasePhenotypePhysiologyPoint MutationPopulation DensityProtease GeneProteasesProtein HomologProteinHomologProteinasesProteinsProteolytic EnzymesProteomicsRNA NucleasesRNaseRegulationReportingRibonuclease Family ProteinRibonucleasesRodRoleShapesSignal PathwaySignal TransductionSignal Transduction PathwaySignal Transduction SystemsSignalingSignaling MoleculeSiteStructureSurfaceSwimmingSystemTechniquesTimeTissue GrowthValidationanaloganti-bacterialaqueousbacterial communitybiofilmbiological signal transductionbiosynthesiscandidate identificationcell biologycircadian clockcircadian pacemakercommunity microbescomplementationcustomsdevelopmentaldiscover genesethyl acetategene discoverygenome mutationgenome segmentgenomic regionheavy metal Pbheavy metal leadhuman-associated microbiomein vivoinsightintercellular communicationknockout genemicrobe communitymicrobialmicrobial communitymicrobial interactionmicrobiomemicrobiome researchmicrobiome sciencemicrobiome studiesmicroorganism communitymicroorganism interactionmutantnovelontogenypathwaypolyclonal antibodypolymicrobial communityprotein crosslinkprotein protein interactionquorum sensingresponsescreeningscreeningssmall moleculesocial roleuptakevalidations

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ABSTRACT
Understanding of the complex network of microbial interactions in the microbiome is integral to human health.

While most microbiome studies have focused on bacterial communities, recent metagenomic analyses report

that archaea comprise a significant percentage of the microbes living in and on our bodies. Yet, little is known

about the…

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Cell-cell signaling in archaea: How Haloferax volcanii talk to each other β€” UNIVERSITY OF PENNSYLVANIA | UNITED STATES | | Dev Procure