CAREER: Uncovering the nature and impact of tumor cell clusters during metastatic migration through the circulatory system

Metastasis is the spread of tumor cells through blood or the lymph system to form new tumors in otherwise healthy organs. Circulating tumor cells (CTCs) in the bloodstream often form clusters of CTCs. Some evidence suggests that when CTCs form clusters, they become more resistant to the body’s immune responses. However, other evidence suggests…