grant
CAREER: Modulating cell signaling and migration by targeted small-molecule binding to a key regulator of protein degradation
Organization Howard UniversityLocation WASHINGTON, United StatesPosted 1 Mar 2025Deadline 31 Mar 2028
NSFUS FederalResearch GrantScience FoundationDC
Description preview
Controlled cell death is key to the removal of unheathy cells but new proteins are being discovered that contribute to the survival of unhealthy cells. The Smith Lab has designed small molecules that bind to a key protein involved in cell survival known as valosin-containing protein (VCP). This project seeks to modulate the function of VCP with…
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