grant
CARE4Kids: Blood Biomarker Core
Organization UNIVERSITY OF CALIFORNIA LOS ANGELESLocation LOS ANGELES, UNITED STATESPosted 8 Sept 2021Deadline 31 Mar 2027
NIHUS FederalResearch GrantFY202612-20 years old18 year old18 years of ageAcuteAdolescenceAdolescentAdolescent YouthAffectAlgorithmsAmericanBiochemicalBiologicalBiological MarkersBloodBlood Reticuloendothelial SystemBlood SampleBlood specimenBrainBrain ConcussionBrain Nervous SystemCaringCategoriesCephalalgiaCephalgiaCephalodyniaCerebral ConcussionClinicalClinical ManagementClinical TreatmentClinical TrialsCollectionCommon Data ElementCommotio CerebriCranial PainDataDedicationsDevelopmentDizzinessEarly identificationEncephalonEvaluationFutureGeneral RadiologyGoalsGroups at riskHead PainHeadacheHuman ResourcesImageInflammationInflammatoryInjuryInterventionInvestigatorsLipidsLong-term disabilityManpowerMeasurementMeasuresMembraneMemoryMethodsMissionMolecularMonitorNINDSNational Institute of Neurological Diseases and StrokeNational Institute of Neurological Disorders and StrokeNerve CellsNerve Impulse TransmissionNerve TransmissionNerve Transmitter SubstancesNerve UnitNeural CellNeural DevelopmentNeurocyteNeuronal TransmissionNeuronsNeuropeptidesNeurotransmittersOrganism-Level ProcessOrganismal ProcessOxidative StressPathway interactionsPeople at riskPeptidesPersons at riskPhenotypePhysiologicPhysiologic ProcessesPhysiologic PsychologyPhysiologicalPhysiological ProcessesPhysiological PsychologyPopulations at RiskPost-Concussion SymptomsPost-Concussion SyndromePost-Concussive SymptomsPost-Concussive SyndromePredicting RiskPreventative interventionProceduresProcessProtein AnalysisProteinsProtocolProtocols documentationPsychophysiologicalPsychophysiologyPublishingQuality ControlR-Series Research ProjectsR01 MechanismR01 ProgramRadiologyRadiology SpecialtyRecoveryReportingReproducibilityResearch GrantsResearch PersonnelResearch Project GrantsResearch ProjectsResearch ResourcesResearchersResourcesRiskSchoolsSiteSpecialtyStandardizationSymptomsTechnical ExpertiseTechniquesTimeTrainingWorkYouthYouth 10-21adolescence (12-20)adult youthage 18age 18 yearsage groupaxon damageaxon injuryaxon signalingaxon-glial signalingaxonal damageaxonal injuryaxonal signalingbio-markersbiobankbiologicbiologic markerbiomarkerbiorepositoryblood-based biomarkerblood-based markerclinical interventionclinical therapycognitive functionconcussionconcussivecritical periodcytokinedata qualitydepositorydesigndesigningdevelopmentaleighteen year oldeighteen years of ageemotional functioningendophenotypeexecutive controlexecutive functionexperiencefallsforecasting riskgenetic analysisglia signalingglial signalinghead achehigh riskimagingimaging biomarkerimaging markerimaging-based biological markerimaging-based biomarkerimaging-based markerimprovedinjuriesintervention for preventionjuvenilejuvenile humanmedical specialtiesmembrane structurenerve signalingneural imagingneural signalingneuro-imagingneurodevelopmentneuroimagingneurological imagingneuronalneuronal signalingneurotransmissionnovelpathwayperipheral bloodpersonnelphysiopsychologypredict riskpredict riskspredicted riskpredicted riskspredicting risksprediction algorithmpredictive riskpredicts riskpreventpreventingprevention interventionpreventional intervention strategypreventive interventionprospectivepsycho-physiologicalrepositoryrisk predictionrisk predictionsrisk stratificationsample collectionsocialspecific biomarkersspecimen collectionstratify risksuccesstargeted drug therapytargeted drug treatmentstargeted therapeutictargeted therapeutic agentstargeted therapytargeted treatmenttechnical skillstraittrial regimentrial treatmentwhite matter changeyoung adultyoung adult ageyoung adulthoodyouth age
Description preview
PROJECT SUMMARY/ABSTRACT – Blood Biomarker Core
Concussions affect nearly 3 million Americans annually (up to 1.9 million under the age of 18), with up to 15-
30% not recovered 3 months after injury. The risk of concussion is 5 times higher among early and middle
adolescents (EMA) than any other age group, highlighting the need to focus on this…
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