grant

Cannabis Legalization a Decade Later: A Longitudinal Study of Teens, Young Adults, and Parents in Washington State

Organization UNIVERSITY OF WASHINGTONLocation SEATTLE, UNITED STATESPosted 1 Jul 2022Deadline 30 Apr 2027
NIHUS FederalResearch GrantFY20250-11 years old21+ years oldAccelerationAddressAdolescentAdolescent YouthAdultAdult ChildrenAdult DaughtersAdult HumanAdult OffspringAdult SonsAffectAgeAlcohol Chemical ClassAlcohol DrinkingAlcohol co-useAlcohol consumptionAlcoholsAttentionBehaviorBindingBiologicalBirthCannabisCannabis retailCare GiversCaregiversChildChild YouthChildren (0-21)CommunitiesCross Sectional AnalysisCross-Sectional AnalysesCross-Sectional StudiesCross-Sectional SurveyDataData CollectionDevelopmentDevelopmental CourseDisease Frequency SurveysDrug usageETOH levelEtOH drinkingEtOH useFamilyFrequenciesFundingGoalsIndividualKnowledgeLegalLife CycleLife Cycle StagesLinkLongitudinal StudiesMarried PersonsMeasuresMethodsModelingMolecular InteractionMorbidityMorbidity - disease rateNicotineOutcomeParentsParturitionPatternPersonsPoliciesPrevalencePreventionProbabilityPublic HealthRecreationResearchRisk FactorsShort WavesSocial DevelopmentSpousesStretchingTHC co-useTHC useTeenTeenagersTetrahydrocannabinol co-useTetrahydrocannabinol useTimeTobacco ConsumptionTobacco useWashingtonWorkYouthYouth 10-21adolescent offspringadult youthadulthoodagesalcohol and other drug usealcohol ingestionalcohol intakealcohol levelalcohol measurementalcohol polysubstance usealcohol product usealcohol usealcoholic beverage consumptionalcoholic drink intakebiologiccannabis legalizationcannabis marketcannabis marketplacecannabis usecannabis use behaviorcannabis use patternscigarette smokingcigarette usecohortdevelopmentaldrug useethanol consumptionethanol drinkingethanol ingestionethanol intakeethanol measurementethanol product useethanol useethyl alcohol measurementsevidence baseintergenerationaljuvenilejuvenile humankidslegal marijuanalegalized cannabislegalized marijuanalife courselong-term studylongitudinal designlongitudinal experimental designlongitudinal outcome studieslongitudinal research designlongitudinal study designmarijuana legalizationmarijuana retailmarijuana usemortalitynicotine consumptionnicotine useoffspringparentpeerpreventpreventingprospectivepsychosocialsell cannabissell marijuanasubstance usesubstance usingteen yearsteenagetheoriestobacco product usevirtualyoung adultyoung adult ageyoung adulthoodyoungsteryouth age
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Full Description

Nonmedical (recreational) cannabis use is now legal in many states. Additional states are considering
legalization, despite the weakness of the current evidence base regarding potential impacts on public health.

This R01 proposal seeks 5 years of funding to understand: Aim 1) changes in cannabis use across the first

decade following cannabis legalization; Aim 2) changes in alcohol use, nicotine use, and their co-use with

cannabis following cannabis legalization; and Aim 3) whether psychosocial consequences of cannabis use

change in a legal cannabis context. This knowledge is critical to inform policy, support efforts to maintain hard-

won reductions in teen cannabis use since the 2000s, and promote responsible use by adults. The proposed

project is grounded in life course theories of development and substance use, and uniquely suited to address

stated goals. It continues and expands upon the Seattle Social Development Project-The Intergenerational

Project (SSDP-TIP), which aims to understand the impact of cannabis legalization on youth and parent

cannabis and other drug use (n = 426 families, 80% living in Washington State). SSDP-TIP includes a parent

drawn from another ongoing longitudinal panel study that began in 1985, their oldest biological child, and a

second caregiver (usually the spouse) when available. Seven waves of pre-legalization data (2002-2011; mean

child age in 2011 = 12) and three waves of short-term post-legalization data (2015-2017; mean child age in

2017 = 18) from offspring and parents are available. The proposed study will add three additional annual data

collections post-legalization in 2022, 2023, and 2024 with parents and offspring (mean offspring age in 2024 =

25; range: 11-36 years). For adolescent offspring, the accelerated longitudinal design allows us to compare

offspring measured before legalization to offspring from later birth cohorts measured at the same ages, but

after legalization. This permits the disentangling of child age and policy effects, and facilitates understanding of

the implications of cannabis legalization for prevention in ways that other studies cannot. The inclusion of

young adult offspring allows examination of the impact of cannabis legalization on patterns of use and

consequences across the 20s and into the early 30s. The inclusion of parents permits examination of post-

legalization changes in cannabis and other drug use and consequences across the 40s. SSDP-TIP is the only

study in Washington State with longitudinal data from youth and their parents beginning 10 years before

legalization. With the proposed data collections, it will also stretch to 12 years post-legalization. This

prospective, longitudinal design provides important advantages over large, repeated cross sectional studies by

enabling causal ordering of legalization and changes in behavior, disentanglement of change due to

legalization versus time or age, and study of both within- and between-person change. Findings will inform the

timing of efforts to prevent underage and problematic cannabis, tobacco, and alcohol use and help to clarify

public health impacts in the context of cannabis legalization.

Grant Number: 5R01DA056371-04
NIH Institute/Center: NIH

Principal Investigator: JENNIFER BAILEY

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