grant

Cancer Genetic and Epigenetic Mechanisms

Organization UNIVERSITY OF WISCONSIN-MADISONLocation MADISON, UNITED STATESPosted 25 Apr 1997Deadline 31 Mar 2028
NIHUS FederalResearch GrantFY2025Advanced CancerAdvanced Malignant NeoplasmArginineBlood DiseasesBreast CancerBudgetsCancer BiologyCancer PatientCancersCatchment AreaCell BodyCellsChromatin Remodeling ComplexChromatin Remodeling FactorClinicalClinical TrialsCollaborationsComprehensive Cancer CenterComputational toolkitData ScientistDiagnosisDiagnosticDiet and NutritionEarly DiagnosisEnrollmentEnsureEnzyme GeneEnzymesEpigeneticEpigenetic ChangeEpigenetic MechanismEpigenetic ProcessEvaluationFaculty RecruitmentFosteringFundingGene ExpressionGene variantGeneralized GrowthGeneticGenetic MedicineGenetic ScreeningGenomeGrantGrowthHematologic DiseasesHematological DiseaseHematological DisorderHematopoietic Cell TumorHematopoietic MalignanciesHematopoietic NeoplasmsHematopoietic Neoplasms including LymphomasHematopoietic TumorHematopoietic and Lymphoid Cell NeoplasmHematopoietic and Lymphoid NeoplasmsHereditaryHumanImmune mediated therapyImmunologically Directed TherapyImmunotherapyInformaticsInheritedInstructionIsoformsKnowledgeL-ArginineLeadLeadershipLicensingLinkMalignant Breast NeoplasmMalignant CellMalignant Hematopoietic NeoplasmMalignant NeoplasmsMalignant TumorMetastasisMetastasizeMetastatic LesionMetastatic MassMetastatic NeoplasmMetastatic TumorMethionineMethylationMissionModern ManMolecular MedicineNeoplasm MetastasisNutritionOncogenesisOncogenicOncologyOncology CancerPatientsPb elementPilot ProjectsPrecision Medicine InitiativePrediction of Response to TherapyPreventionProductivityProtein IsoformsProteinsPublicationsResearchScientific PublicationSecondary NeoplasmSecondary TumorStrategic PlanningStructureSystemTechnologyTextTherapeuticTissue GrowthTranslatingTranslational ResearchTranslational ScienceTranslationsVariantVariationallelic variantanti-cancer researchbench bed sidebench bedsidebench to bed sidebench to bedsidebench to clinicbench to clinical practicebiomarker performancebiomarker utilityblood cancerblood disordercancer cellcancer diagnosiscancer geneticscancer metastasiscancer of bloodcancer of the bloodcancer predispositioncancer preventioncancer researchcancer riskcancer typechromatin modifierchromatin remodelingclinical diagnosticsclinical practicecomputational toolboxcomputational toolscomputational toolsetcomputerized toolsdata infrastructuredata sharingearly detectionenrollepigenetic therapyepigeneticallyepigenomefaculty mentorforginggenetic variantgenome sequencinggenomic variantheavy metal Pbheavy metal leadimmune therapeutic approachimmune therapeutic interventionsimmune therapeutic regimensimmune therapeutic strategyimmune therapyimmune-based therapiesimmune-based treatmentsimmuno therapyimprovedindividualized cancer careindividualized oncologyinformatics shared resourceinnovateinnovationinnovativeinnovative technologiesinter-institutionalinterdisciplinary collaborationinventionmalignancymalignant breast tumormedical diagnosticmeetingmeetingsmembermodel organismmultidisciplinarymultiomicsmultiple omicsneoplasm/canceroncohistoneontogenypanomicspersonalized oncologypilot studyprecision cancer careprecision cancer medicineprecision medicineprecision medicine clinical trialsprecision oncologyprecision-based medicinepredict therapeutic responsepredict therapy responsepredictive biological markerpredictive biomarkerspredictive markerpredictive molecular biomarkerprofessorprogramsprospectiverecruitrecruit teachersresponse to therapyresponse to treatmentteacher recruitmenttechnological innovationtherapeutic responsetherapeutic targettherapy predictiontherapy responsetooltransdisciplinary collaborationtranslationtranslation researchtranslation strategytranslational approachtranslational goaltranslational investigationtranslational investigatortranslational missiontranslational opportunitiestranslational potentialtranslational researchertranslational scientisttranslational strategytreatment predictiontreatment responsetreatment response predictiontreatment responsivenesstumortumor DNAtumor cell DNAtumor cell metastasistumor-specific DNAtumorigenesis
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UWCCC CANCER GENETIC AND EPIGENETIC MECHANISMS PROGRAM SUMMARY
Co-Leaders: Emery Bresnick and Wei Xu

Cancer arises from disruption of genome and epigenome structure and function. Understanding genetic and

epigenetic mechanisms and their aberrations will advance cancer prevention, diagnosis, and treatment. The

mission of the Cancer Genetic and…

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Cancer Genetic and Epigenetic Mechanisms — UNIVERSITY OF WISCONSIN-MADISON | UNITED STATES | Apr 1997 | Dev Procure