grant

BRITE 2.0: A just-in-time adaptive intervention for suicide safety planning in adolescents

Organization KSANA HEALTH, INC.Location EUGENE, UNITED STATESPosted 15 Apr 2024Deadline 31 Oct 2026
NIHUS FederalResearch GrantFY2026AddressAdolescentAdolescent YouthAndroid AppAndroid ApplicationBenchmarkingBest Practice AnalysisCause of DeathCell PhoneCell Phone ApplicationCell phone AppCellular PhoneCellular Phone AppCellular Phone ApplicationCellular TelephoneCollaborationsComputer Software DevelopmentComputer Software EngineeringCoping SkillsDevelopmentDissemination and ImplementationDistressDoseEcological momentary assessmentEffectivenessEvaluationEvidence based interventionFaceFeeling suicidalFutureHealthIndividualInterventionInvestigatorsJust-in-Time Adaptive InterventionMethodsMobile PhonesMonitorNotificationParentsPatientsPhasePragmatic clinical trialRandomization trialRandomizedRecommendationResearchResearch PersonnelResearch ResourcesResearchersResourcesRiskSBIRSafetySelf EfficacySmall Business Innovation ResearchSmall Business Innovation Research GrantSmart Phone AppSmart Phone ApplicationSmartphone AppSoftware EngineeringSuggestionSuicidal thoughtsSuicideSuicide attemptSuicide precautionSuicide preventionTestingTimeUniversitiesYouthYouth 10-21app on a smartphoneapplication on a smartphoneassess effectivenessautomated algorithmautomatic algorithmbenchmarkbrief interventionbrief therapybrief treatmentcare providerscell phone based appcommercializationcoping strategydetermine effectivenessdevelopmentaldigital mental healthdigital tooldigital toolkiteffective interventioneffectiveness assessmenteffectiveness clinical trialeffectiveness evaluationemotional distressevaluate effectivenessevidence baseexamine effectivenessfacesfacialfatal attemptfatal suicidefeeling distressfeeling upsethigh riskiOS appiOS applicationiPhoneiPhone AppiPhone Applicationimprovedintent to diejuvenilejuvenile humanmeetingmeetingsmobile phone appmobile sensingnon fatal attemptnonfatal attemptparentparticipant engagementpatient engagementphone appphone applicationprevent suicidalityprevent suicideproduct developmentprotective factorsrandomisationrandomizationrandomized trialrandomly assignedreduce suicidalityreduce suicidereducing suicidalityreducing suicideresponsesmart phonesmartphonesmartphone applicationsmartphone based appsmartphone based applicationsuccesssuicidal attemptsuicidal behaviorsuicidal ideationsuicidal risksuicidal thinkingsuicidality preventionsuicide behaviorsuicide ideationsuicide interventionsuicide ratesuicide risksuicidestherapy optimizationthoughts about suicidetreatment optimizationusabilityweb sitewebsiteyouth age
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Full Description

ABSTRACT
Despite efforts to prevent suicide, US rates are climbing, and suicide is the second leading cause of death

amongst youth. While suicide safety planning interventions can be effective in reducing suicidal behavior,

adolescents often face challenges in sustaining their engagement with them. Studies have found that many

adolescents do not review their safety plans or attempt to use coping strategies following discharge. Digital

tools can provide a powerful means to enhance engagement with these interventions. The overall aim of this

SBIR Fast Track proposal is to enhance the effectiveness of safety planning amongst at risk youth by

developing and commercializing an augmented version of the BRITE smartphone app that provides enhanced

features that will optimize effectiveness by addressing known barriers to user engagement. The BRITE app

facilitates self-efficacy by encouraging self-monitoring of emotional distress and utilization of effective coping

strategies as well as providing ready access to a safety plan on the adolescent’s smartphone. The BRITE app

was developed on evidence-based principles and has undergone rigorous formative development and

effectiveness evaluations. However, to optimize its functionality, commercial viability, and scale its

implementation, issues related to user engagement need to be addressed. Recent developments in Ecological

Momentary Assessment (EMA) and mobile sensing (MS) can provide useful triggers to automatically “push”

pertinent safety planning information to individuals during periods of higher risk, which will allow the integration

of just-in-time adaptive intervention features within BRITE and should result in more sustained engagement

with the plan and increased effectiveness. In Phase I we will develop an augmented version of the BRITE app

(BRITE 2.0) that integrates just-in-time automated push notifications for consistent practice of coping skills and

for safety planning resources during periods of escalating risk, and will evaluate the usability and acceptability

of this product with practitioners and end users. The aim of Phase II is to conduct a micro randomized trial to

optimize treatment components, and to conduct an initial RCT to evaluate whether these enhancements

increase user engagement.

Grant Number: 5R44MH135605-03
NIH Institute/Center: NIH

Principal Investigator: NICHOLAS ALLEN

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