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Bringing PFAS Monitoring Home: An Integrated Magnetic Nanoparticle and Lateral Flow Assay System

Organization BIOTA INC.Location FORT COLLINS, UNITED STATESPosted 1 Aug 2025Deadline 31 Jan 2026 ⚠️
NIHUS FederalResearch GrantFY20255-IsothiocyanatofluoresceinAddressAg elementAmericanAmmoniumAntibodiesAssayBindingBioassayBiological AssayBloodBlood Reticuloendothelial SystemBuffersCancersCell Communication and SignalingCell SignalingChemicalsConsumptionCristobaliteDataDetectionDevelopmentDevicesDiagnosticDiagnostic DeviceDiagnostic EquipmentDiagnostic testsDysfunctionEcologic MonitoringEcological MonitoringEnsureEnvironmental MonitoringEnvironmental PollutantsEnvironmental ToxinExposure toFITCFe oxideFluorescein-5-isothiocyanateFoundationsFunctional disorderFutureGoalsHPLCHealthHealth Care TechnologyHealth TechnologyHigh Performance Liquid ChromatographyHigh Pressure Liquid ChromatographyHigh Speed Liquid ChromatographyHomeIndividualInjury to LiverIntracellular Communication and SignalingL-ThyroxineLateralLevothyroxineLinkMagnetic nanoparticlesMalignant NeoplasmsMalignant TumorMarketingMeasuresMethodsMissionMolecular InteractionMonitorNoiseOutcomePerformancePhasePhysiopathologyPrealbuminProalbuminProteinsPublic HealthRegulationResearchRiskSandSignal TransductionSignal Transduction SystemsSignalingSilicaSilicon DioxideSilverSystemT4 Thyroid HormoneTailTechnologyTestingTherapeutic LevothyroxineThyroidThyroid Function TestsThyroid GlandThyroid Gland Function TestsThyroid Head and NeckThyroxineTimeToxic Environmental AgentsToxic Environmental SubstancesToxic effectToxicitiesTransthyretinTridymiteWorkbiological signal transductionchemical groupcolcotharconsumer demandcostdetection limitdetection testdetection testsdevelopmentaldevelopmental toxicitydiagnostic technologiesdrinking waterempowermentenvironmental contaminantenvironmental testingenvironmental toxicantferric oxidehepatic damagehepatic injuryhome based monitoringhome monitoringhomesimprovedindexinginnovateinnovationinnovativeinsightiron oxidelateral flow assaylateral flow testliver damageliver injurymalignancymanufacturenano particlenano-sized particlenanoparticlenanosized particleneoplasm/cancernoveloperationoperationsparticlepathophysiologyperformance testspollutantpreservationprototypered iron oxidethyroid disruptionthyroid functionthyroid hormone disruptionthyroxintooluser-friendlyvalidation studiesvulnerable communitywater sampling

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PROJECT SUMMARY/ABSTRACT
Per- and polyfluoroalkyl substances (PFAS) are persistent environmental contaminants linked to severe health issues, including thyroid dysfunction, cancer, and developmental toxicity. Detected in the blood of 97% of Americans, PFAS exposure poses a critical public health challenge, prompting the EPA to establish stringent…

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